Protein Alignment CG1698 and Slc6a5

DIOPT Version :9

• Sequence 1: NP_001260835.1
• Gene: CG1698 / 36006
• FlyBaseID: FBgn0033443
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_976079.1
• Gene: Slc6a5 / 171148
• RGDID: 621824
• Length: 799
• Species: Rattus norvegicus
• Alignment Length: 666
• Identity: 235/666 - (35%)
• Similarity: 358/666 - (53%)
• Gaps: 87/666 - (13%)

  Fly    21 GSLNASTISIPGAYKPNESSN---GKKTLSEGSGSAPPPGHGDS----------------PSGV- 65
            |:.||....||....|.|..|   .|.||..  .:.||.|..:.                |..|
  Rat   115 GAGNALHCKIPALRGPEEDENVSVAKGTLEH--NNTPPVGWVNMSQSTVVLGTDGIASVLPGSVA 177

  Fly    66 -------EAGQPGKKRDSWNNDIEFLMSCIALSVGLGNVWRFPFTALENGGGAFVIPYLIVLILV 123
                   |.|...|.|.:|::.::|::|.:..:||||||||||:.|.:||||||:||||::|.|.
  Rat   178 TTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALA 242

  Fly   124 GKPVYYLEMLLGQFSSRGSVKVYDFSPIMRGIGYGQVLATGIVTTYYATLMALTLRYFVDSFYPT 188
            |.|:::||:.||||:|:|.|.|:...|.::|.|...::.:.::..||..::..||.|...||...
  Rat   243 GLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSV 307

  Fly   189 LPWSYCREEWGT-EC-------LDS---GPQE----------------------ASRATSLAGSG 220
            |||..|...|.| ||       |||   |...                      .|:|.....||
  Rat   308 LPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQANKTFVSG 372

  Fly   221 VRTTSAEFYFTNIILREKASIDDGIGYPS---WSLALALAVAWIVIAGIMFKGVKSSGKASYFLA 282
                 :|.||...:|:    |..||.||.   |.|...|.:||:::...:.||:|:|||..||.|
  Rat   373 -----SEEYFKYFVLK----ISAGIEYPGEIRWPLPFCLFLAWVIVYASLAKGIKTSGKVVYFTA 428

  Fly   283 LFPYVVMLVLLVRALTLPGAFDGVLYFLRPQWHKLLEPQVWYAAVTQVFFSLAICFGNIIMYASY 347
            .|||||:::||:|.:|||||..|:.||:.|:|.||.:..||..|.||:||||:..:|.:|..:||
  Rat   429 TFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSY 493

  Fly   348 NRFGHNIYRDANIVTTLDTFTSLLSGVIIFGILGNLAYENNTTDIASVVNGGPGLAFISYPDAIA 412
            |:|.:|.|||..|||..::.||:.:|.:||.::|.:|.|.. .:|.:|.:.|||:||:.||:|:.
  Rat   494 NKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERK-VNIENVADQGPGIAFVVYPEALT 557

  Fly   413 KFKWLPQLFSVLFFLMLFVLGIGSNVGMASCMSTVIKDQF-GHLKNWTVV--VGIAIVGYFLGLL 474
            :....| .::::|||||..||:.:.......:.|.|.|:| .:|:....|  :|..|..:.:|..
  Rat   558 RLPLSP-FWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFP 621

  Fly   475 YITPGGQFLLNLVDYFGVTFVALVLAIFELVTIAWIYGVKRLCRDVEFMIGIKTSLYYRICWAVV 539
            .||.||.::..|||.:..::..:::||||||.|:::||::|.|.|:|.|||.:.::::::|||.|
  Rat   622 MITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFV 686

  Fly   540 TPLLMLTILIYTLVLYEPLKYKDYTYQSGVYVFGWCLSAFGVGQVLFWAIPAVRKQPSHLG---L 601
            ||.::..||.::...:||:.|..|.|.:...|.||.:.|..|    .| ||.:.....:|.   .
  Rat   687 TPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSV----IW-IPIMFVIKMYLAPGRF 746

  Fly   602 WARIRKAFEPLPNWGP 617
            ..|::....|.|:|||
  Rat   747 IERLKLVCSPQPDWGP 762

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1698	NP_001260835.1	SLC6sbd	75..552	CDD:271359	195/515 (38%)
Slc6a5	NP_976079.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..64
		SLC6sbd_GlyT2	193..789	CDD:271389	216/586 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920