Protein Alignment CG1698 and Slc6a5

DIOPT Version :10

• Sequence 1: NP_610517.1
• Gene: CG1698 / 36006
• FlyBaseID: FBgn0033443
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: XP_063131123.1
• Gene: Slc6a5 / 171148
• RGDID: 621824
• Length: 812
• Species: Rattus norvegicus
• Alignment Length: 674
• Identity: 235/674 - (34%)
• Similarity: 360/674 - (53%)
• Gaps: 103/674 - (15%)

  Fly    21 GSLNASTISIPGAYKPNESSN---GKKTLSEGSGSAPPPGHGDSPS----------------GV- 65
            |:.||....||....|.|..|   ||.||.          |.::|:                |:
  Rat   128 GAGNALHCKIPALRGPEEDENVSVGKGTLE----------HNNTPAVGWVNMSQSTVVLGTDGIA 182

  Fly    66 ---------------EAGQPGKKRDSWNNDIEFLMSCIALSVGLGNVWRFPFTALENGGGAFVIP 115
                           |.|...|.|.:|::.::|::|.:..:||||||||||:.|.:||||||:||
  Rat   183 SVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIP 247

  Fly   116 YLIVLILVGKPVYYLEMLLGQFSSRGSVKVYDFSPIMRGIGYGQVLATGIVTTYYATLMALTLRY 180
            ||::|.|.|.|:::||:.||||:|:|.|.|:...|.::|.|...::.:.::..||..::..||.|
  Rat   248 YLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFY 312

  Fly   181 FVDSFYPTLPWSYCREEWGT-EC-------LDS---GPQE----------------------ASR 212
            ...||...|||..|...|.| ||       |||   |...                      .|:
  Rat   313 LFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQ 377

  Fly   213 ATSLAGSGVRTTSAEFYFTNIILREKASIDDGIGYPS---WSLALALAVAWIVIAGIMFKGVKSS 274
            |.....||     :|.||...:|:    |..||.||.   |.||..|.:||:::...:.||:|:|
  Rat   378 ANKTFVSG-----SEEYFKYFVLK----ISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKTS 433

  Fly   275 GKASYFLALFPYVVMLVLLVRALTLPGAFDGVLYFLRPQWHKLLEPQVWYAAVTQVFFSLAICFG 339
            ||..||.|.|||||:::||:|.:|||||..|:.||:.|:|.||.:..||..|.||:||||:..:|
  Rat   434 GKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWG 498

  Fly   340 NIIMYASYNRFGHNIYRDANIVTTLDTFTSLLSGVIIFGILGNLAYENNTTDIASVVNGGPGLAF 404
            .:|..:|||:|.:|.|||..|||..::.||:.:|.:||.::|.:|.|.. .:|.:|.:.|||:||
  Rat   499 GLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERK-VNIENVADQGPGIAF 562

  Fly   405 ISYPDAIAKFKWLPQLFSVLFFLMLFVLGIGSNVGMASCMSTVIKDQF-GHLKNWTVV--VGIAI 466
            :.||:|:.:....| .::::|||||..||:.:.......:.|.|.|:| .:|:....|  :|..|
  Rat   563 VVYPEALTRLPLSP-FWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCI 626

  Fly   467 VGYFLGLLYITPGGQFLLNLVDYFGVTFVALVLAIFELVTIAWIYGVKRLCRDVEFMIGIKTSLY 531
            ..:.:|...||.||.::..|||.:..::..:::||||||.|:::||::|.|.|:|.|||.:.:::
  Rat   627 CFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIF 691

  Fly   532 YRICWAVVTPLLMLTILIYTLVLYEPLKYKDYTYQSGVYVFGWCLSAFGVGQVLFWAIPAVRKQP 596
            :::|||.|||.::..||.::...:||:.|..|.|.:...|.||.:.|..|    .| ||.:....
  Rat   692 WKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSV----IW-IPIMFVIK 751

  Fly   597 SHLG---LWARIRKAFEPLPNWGP 617
            .:|.   ...|::....|.|:|||
  Rat   752 MYLAPGRFIERLKLVCSPQPDWGP 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1698	NP_610517.1	SLC6sbd	75..552	CDD:271359	196/515 (38%)
Slc6a5	XP_063131123.1	None