DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1698 and Slc6a9

DIOPT Version :9

Sequence 1:	NP_001260835.1	Gene:	CG1698 / 36006	FlyBaseID:	FBgn0033443	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_001342104.1	Gene:	Slc6a9 / 14664	MGIID:	95760	Length:	652	Species:	Mus musculus

Alignment Length:	593	Identity:	214/593 - (36%)
Similarity:	346/593 - (58%)	Gaps:	28/593 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 SEGSGSAP-PPGHGDSPSGVEAGQPGKKRDSWNNDIEFLMSCIALSVGLGNVWRFPFTALENGGG 110
            ::|..:.| |..:|..||..........|.:|.|.|||:::.:..:||||||||||:....||||
Mouse    18 AQGPVATPSPEQNGAVPSEATKKDQNLTRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGG 82

  Fly   111 AFVIPYLIVLILVGKPVYYLEMLLGQFSSRGSVKVYDFSPIMRGIGYGQVLATGIVTTYYATLMA 175
            ||:.||.|:||..|.|::::|:..|||:|:|.:.|:..||:.:|:|||.::.:..:..||..::.
Mouse    83 AFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVIC 147

  Fly   176 LTLRYFVDSFYPTLPWSYCREEWGT-EC---LD-SGPQEASRATSLAG--------SGVRTTSAE 227
            :...||..|....|||:||...|.| :|   || |.....||..:|:|        :..||:.:|
Mouse   148 IAFYYFFSSMTHVLPWAYCNNPWNTPDCAGVLDASNLTNGSRPAALSGNLSHLFNYTLQRTSPSE 212

  Fly   228 FYFTNIILREKASIDDGIG-YPSWSLAL--ALAVAWIVIAGIMFKGVKSSGKASYFLALFPYVVM 289
            .|:...:|:    :.|.|| :....|.|  .|.|:|:|:...:.:|||||||..||.|.|||||:
Mouse   213 EYWRLYVLK----LSDDIGNFGEVRLPLLGCLGVSWVVVFLCLIRGVKSSGKVVYFTATFPYVVL 273

  Fly   290 LVLLVRALTLPGAFDGVLYFLRPQWHKLLEPQVWYAAVTQVFFSLAICFGNIIMYASYNRFGHNI 354
            .:|.||.:||.|||.|::|:|.|||.|:||.:||..|.:|:|:||...:|.:|..||||:|.:|.
Mouse   274 TILFVRGVTLEGAFTGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNC 338

  Fly   355 YRDANIVTTLDTFTSLLSGVIIFGILGNLAYENNTTDIASVVNGGPGLAFISYPDAIAKFKWLPQ 419
            |||:.|::..:..||:.:|.:||.|||.:| .:...|::.|.:.||||||::||:|:......|
Mouse   339 YRDSVIISITNCATSVYAGFVIFSILGFMA-NHLGVDVSRVADHGPGLAFVAYPEALTLLPISP- 401

  Fly   420 LFSVLFFLMLFVLGIGSNVGMASCMSTVIKDQFGH----LKNWTVVVGIAIVGYFLGLLYITPGG 480
            |:|:|||.||.:||:|:...:...:.|.|.|:.|:    .|...|.:|:|:.|:.||:...:..|
Mouse   402 LWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAG 466

  Fly   481 QFLLNLVDYFGVTFVALVLAIFELVTIAWIYGVKRLCRDVEFMIGIKTSLYYRICWAVVTPLLML 545
            .:.|.|:|.:..:|..:|::....|:|.:|||.:...:|::.|:|....|:::|||..|:|.::.
Mouse   467 IYWLLLMDNYAASFSLVVISCIMCVSIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIF 531

  Fly   546 TILIYTLVLYEPLKYKDYTYQSGVYVFGWCLSAFGVGQVLFWAIPAVRKQPSHLGLWARIRKAFE 610
            .|||:|::.|.|:.|..|.|.......|:.::...|..:..:|:..:.:..... |..|::.|.:
Mouse   532 FILIFTVIQYRPITYNHYQYPGWAVAIGFLMALSSVICIPLYALFQLCRTDGDT-LLQRLKNATK 595

  Fly   611 PLPNWGPS 618
            |..:|||:
Mouse   596 PSRDWGPA 603

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1698	NP_001260835.1	SLC6sbd	75..552	CDD:271359	191/496 (39%)
Slc6a9	NP_001342104.1	SLC6sbd_GlyT1	30..613	CDD:212067	211/581 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820