DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1698 and Slc6a13

DIOPT Version :9

Sequence 1:	NP_001260835.1	Gene:	CG1698 / 36006	FlyBaseID:	FBgn0033443	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_001366036.1	Gene:	Slc6a13 / 14412	MGIID:	95629	Length:	602	Species:	Mus musculus

Alignment Length:	573	Identity:	208/573 - (36%)
Similarity:	320/573 - (55%)	Gaps:	36/573 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 KRDSWNNDIEFLMSCIALSVGLGNVWRFPFTALENGGGAFVIPYLIVLILVGKPVYYLEMLLGQF 137
            :|:.|||.:||::|.....:|||||||||:...:||||||.|||||.|...|.||::||..|||:
Mouse    31 EREHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQY 95

  Fly   138 SSRGSVKVY-DFSPIMRGIGYGQVLATGIVTTYYATLMALTLRYFVDSFYPTLPWSYCREEWGTE 201
            :::|.:..: ...||..||||...:...::..||..::|..|.|...||...|||..|..||.||
Mouse    96 TNQGGITAWRRICPIFEGIGYASQMIVSLLNVYYIVVLAWALFYLFSSFTTDLPWGSCSHEWNTE 160

  Fly   202 -CLDSGPQEASRATSLAGSGVRTTSAEFYFTNIILREKASIDDGI---GYPSWSLALALAVAWIV 262
             |::.  |:|:.:.::......:...||:...::     .:.|||   |...|.|.|.|.:|||:
Mouse   161 NCVEF--QKANDSMNVTSENATSPVIEFWERRVL-----KLSDGIQHLGSLRWELVLCLLLAWII 218

  Fly   263 IAGIMFKGVKSSGKASYFLALFPYVVMLVLLVRALTLPGAFDGVLYFLRPQWHKLLEPQVWYAAV 327
            ....::|||||:||..||.|.|||::::|||:|.:|||||..|:.::|.|...:|.:||||..|.
Mouse   219 CYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQFYLYPNITRLWDPQVWMDAG 283

  Fly   328 TQVFFSLAICFGNIIMYASYNRFGHNIYRDANIVTTLDTFTSLLSGVIIFGILGNLAYENNTTDI 392
            ||:|||.|||.|.:....|||::.:|.|||...:..|::.||.::|..||.|||.::.|.. ..|
Mouse   284 TQIFFSFAICLGCLTALGSYNKYHNNCYRDCIALCILNSSTSFMAGFAIFSILGFMSQEQG-VPI 347

  Fly   393 ASVVNGGPGLAFISYPDAIAKFKWLPQLFSVLFFLMLFVLGIGSNVGMASCMSTVIKDQFGHL-- 455
            :.|...|||||||:||.|:....:.| |::..||.|:.:||:.|.......:.|.:.|.:..:
Mouse   348 SEVAESGPGLAFIAYPRAVVMLPFSP-LWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPRVFR 411

  Fly   456 ---KNWTVVVGIAIVGYFLGLLYITPGGQFLLNLVDYFGVTFVALV-LAIFELVTIAWIYGVKRL 516
               :...:::.::::.:|:||:.:|.||.::..|.||:..:.:.|: :||||.:.:||:||..|.
Mouse   412 KKNRREVLILIVSVISFFIGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGAGRF 476

  Fly   517 CRDVEFMIGIKTSLYYRICWAVVTPLLMLTILIYTLVLYEPLKY-KDYTYQSGVYVFGWCLSAFG 580
            ..::|.|||.|.....:.||...||.:.|...:::|:.|.||.| |.|||.......||.|:...
Mouse   477 YDNIEDMIGYKPWPLIKYCWLFFTPAVCLATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSS 541

  Fly   581 VGQVLFWAIPAVR--KQPSHLGLWARIRKAF---EPLPN------WGPSDPQT 622
            :..:..|:|..:|  |.|    |..|:|:..   |.||.      ..|:.|.|
Mouse   542 MICIPAWSIYKLRTLKGP----LRERLRQLVCPAEDLPQKNQPEPTAPATPMT 590

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1698	NP_001260835.1	SLC6sbd	75..552	CDD:271359	181/487 (37%)
Slc6a13	NP_001366036.1	SLC5-6-like_sbd	32..575	CDD:382020	203/555 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820