Protein Alignment CG1698 and Slc6a3

DIOPT Version :9

• Sequence 1: NP_001260835.1
• Gene: CG1698 / 36006
• FlyBaseID: FBgn0033443
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_034150.1
• Gene: Slc6a3 / 13162
• MGIID: 94862
• Length: 619
• Species: Mus musculus
• Alignment Length: 569
• Identity: 199/569 - (34%)
• Similarity: 320/569 - (56%)
• Gaps: 25/569 - (4%)

  Fly    31 PGAYKPNE-------SSNGKKTLSEGSGSAPPPGHGDSPSGVEAGQPGKKRDSWNNDIEFLMSCI 88
            |.|..|.|       ..||.: |:..:...||    .:|..|:      :|::|:..|:||:|.|
Mouse    21 PNAVGPREVELILVKEQNGVQ-LTNSTLINPP----QTPVEVQ------ERETWSKKIDFLLSVI 74

  Fly    89 ALSVGLGNVWRFPFTALENGGGAFVIPYLIVLILVGKPVYYLEMLLGQFSSRGSVKVYDFSPIMR 153
            ..:|.|.||||||:...:||||||::|||:.:::.|.|::|:|:.||||:..|:..|:...|:::
Mouse    75 GFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELALGQFNREGAAGVWKICPVLK 139

  Fly   154 GIGYGQVLATGIVTTYYATLMALTLRYFVDSFYPTLPWSYCREEWGT-ECLDSGPQEASRATSLA 217
            |:|:..:|.:..|..:|..::|..|.||..||...|||.:|...|.: .|.|:....:|....|.
Mouse   140 GVGFTVILISFYVGFFYNVIIAWALHYFFSSFTMDLPWIHCNNTWNSPNCSDAHSSNSSDGLGLN 204

  Fly   218 GSGVRTTSAEFYFTNII-LREKASIDDGIGYPSWSLALALAVAWIVIAGIMFKGVKSSGKASYFL 281
            .:...|.:||::...:: |.:...||| :|.|.|.|...|.:..:::...::||||:|||..:..
Mouse   205 DTFGTTPAAEYFERGVLHLHQSRGIDD-LGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWIT 268

  Fly   282 ALFPYVVMLVLLVRALTLPGAFDGVLYFLRPQWHKLLEPQVWYAAVTQVFFSLAICFGNIIMYAS 346
            |..||||:..||:|.:|||||.||:..:|...:::|.|..||..|.|||.|||.:.||.:|.::|
Mouse   269 ATMPYVVLTALLLRGVTLPGAMDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSS 333

  Fly   347 YNRFGHNIYRDANIVTTLDTFTSLLSGVIIFGILGNLAYENNTTDIASVVNGGPGLAFISYPDAI 411
            ||:|.:|.||||.|.|::::.||..||.::|..||.:|.::| ..|..|...||||.||.||:||
Mouse   334 YNKFTNNCYRDAIITTSINSLTSFSSGFVVFSFLGYMAQKHN-VPIRDVATDGPGLIFIIYPEAI 397

  Fly   412 AKFKWLPQLFSVLFFLMLFVLGIGSNVGMASCMSTVIKDQFG--HLKNWTVVVGIAIVGYFLGLL 474
            |... |...::.:|||||..|||.|.:|....:.|.:.|:|.  |.......:||.:..:.|.|.
Mouse   398 ATLP-LSSAWAAVFFLMLLTLGIDSAMGGMESVITGLVDEFQLLHRHRELFTLGIVLATFLLSLF 461

  Fly   475 YITPGGQFLLNLVDYFGVTFVALVLAIFELVTIAWIYGVKRLCRDVEFMIGIKTSLYYRICWAVV 539
            .:|.||.::..|:|:|......|...:.|.:.:||.|||::...|::.|.|.:.:||:|:||.:|
Mouse   462 CVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVQQFSDDIKQMTGQRPNLYWRLCWKLV 526

  Fly   540 TPLLMLTILIYTLVLYEPLKYKDYTYQSGVYVFGWCLSAFGVGQVLFWA 588
            :|..:|.:::.::|.:.|..|..|.:.......||.::...:..|..:|
Mouse   527 SPCFLLYVVVVSIVTFRPPHYGAYIFPDWANALGWIIATSSMAMVPIYA 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1698	NP_001260835.1	SLC6sbd	75..552	CDD:271359	179/480 (37%)
Slc6a3	NP_034150.1	SLC5-6-like_sbd	60..613	CDD:294310	188/519 (36%)
		Interaction with TGFB1I1. /evidence=ECO:0000250	560..589		4/16 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820