DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1698 and Slc6a9

DIOPT Version :9

Sequence 1:	NP_001260835.1	Gene:	CG1698 / 36006	FlyBaseID:	FBgn0033443	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	XP_006238687.1	Gene:	Slc6a9 / 116509	RGDID:	621243	Length:	638	Species:	Rattus norvegicus

Alignment Length:	584	Identity:	210/584 - (35%)
Similarity:	341/584 - (58%)	Gaps:	21/584 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 SAPPPGHGDSPSGVEAGQPGKKRDSWNNDIEFLMSCIALSVGLGNVWRFPFTALENGGGAFVIPY 116
            ::.|..:|..||..........|.:|.|.|||:::.:..:||||||||||:....||||||:.||
  Rat    10 TSSPEQNGAVPSEATKKDQNLTRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPY 74

  Fly   117 LIVLILVGKPVYYLEMLLGQFSSRGSVKVYDFSPIMRGIGYGQVLATGIVTTYYATLMALTLRYF 181
            .|:|:..|.|::::|:..|||:|:|.:.|:..||:.:|:|||.::.:..:..||..::.:...||
  Rat    75 FIMLVFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYF 139

  Fly   182 VDSFYPTLPWSYCREEWGT-EC---LD-SGPQEASRATSLAG--------SGVRTTSAEFYFTNI 233
            ..|....|||:||...|.| :|   || |.....||.|:|:|        :..||:.:|.|:...
  Rat   140 FSSMTHVLPWAYCNNPWNTPDCAGVLDASNLTNGSRPTALSGNLSHLFNYTLQRTSPSEEYWRLY 204

  Fly   234 ILREKASIDDGIGYPSWSLALALAVAWIVIAGIMFKGVKSSGKASYFLALFPYVVMLVLLVRALT 298
            :|:....|.| .|.....|...|.|:|:|:...:.:|||||||..||.|.|||||:.:|.||.:|
  Rat   205 VLKLSDDIGD-FGEVRLPLLGCLGVSWVVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVT 268

  Fly   299 LPGAFDGVLYFLRPQWHKLLEPQVWYAAVTQVFFSLAICFGNIIMYASYNRFGHNIYRDANIVTT 363
            |.|||.|::|:|.|:|.|:||.:||..|.:|:|:||...:|.:|..||||:|.:|.|||:.|::.
  Rat   269 LEGAFTGIMYYLTPKWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISI 333

  Fly   364 LDTFTSLLSGVIIFGILGNLAYENNTTDIASVVNGGPGLAFISYPDAIAKFKWLPQLFSVLFFLM 428
            .:..||:.:|.:||.|||.:| .:...|::.|.:.||||||::||:|:......| |:|:|||.|
  Rat   334 TNCATSVYAGFVIFSILGFMA-NHLGVDVSRVADHGPGLAFVAYPEALTLLPISP-LWSLLFFFM 396

  Fly   429 LFVLGIGSNVGMASCMSTVIKDQFGH----LKNWTVVVGIAIVGYFLGLLYITPGGQFLLNLVDY 489
            |.:||:|:...:...:.|.|.|:.|:    .|...|.:|:|:.|:.||:...:..|.:.|.|:|.
  Rat   397 LILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDN 461

  Fly   490 FGVTFVALVLAIFELVTIAWIYGVKRLCRDVEFMIGIKTSLYYRICWAVVTPLLMLTILIYTLVL 554
            :..:|..:|::....|:|.:|||.:...:|::.|:|....|:::|||..|:|.::..|||:|::.
  Rat   462 YAASFSLVVISCIMCVSIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPTIIFFILIFTVIQ 526

  Fly   555 YEPLKYKDYTYQSGVYVFGWCLSAFGVGQVLFWAIPAVRKQPSHLGLWARIRKAFEPLPNWGPS 618
            |.|:.|..|.|.......|:.::...|..:..:|:..:.:..... |..|::.|.:|..:|||:
  Rat   527 YRPITYNHYQYPGWAVAIGFLMALSSVICIPLYALFQLCRTDGDT-LLQRLKNATKPSRDWGPA 589

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1698	NP_001260835.1	SLC6sbd	75..552	CDD:271359	189/493 (38%)
Slc6a9	XP_006238687.1	SLC6sbd_GlyT1	16..599	CDD:212067	209/578 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820