Protein Alignment CG1698 and slc6a4

DIOPT Version :9

• Sequence 1: NP_001260835.1
• Gene: CG1698 / 36006
• FlyBaseID: FBgn0033443
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: XP_017946918.1
• Gene: slc6a4 / 100493853
• XenbaseID: XB-GENE-22062972
• Length: 664
• Species: Xenopus tropicalis
• Alignment Length: 587
• Identity: 208/587 - (35%)
• Similarity: 324/587 - (55%)
• Gaps: 51/587 - (8%)

  Fly    35 KPNESSNGKKTLSEGSGSAPPPG------HGDSPS--------------GVEAGQPGKKRDSWNN 79
            :|...||  |.|:..|..||..|      .|.:|:              ..|.|:    |::|:.
 Frog    60 EPGHISN--KYLAVQSPEAPCNGMRNGGDEGSTPTLTVLPACRAEIQHLQTEIGE----RETWSK 118

  Fly    80 DIEFLMSCIALSVGLGNVWRFPFTALENGGGAFVIPYLIVLILVGKPVYYLEMLLGQFSSRGSVK 144
            .|:||:|.|..:|.||||||||:...:||||||:|||:|:.:..|.|::|:|:.:||:...|.:.
 Frog   119 KIDFLLSVIGYAVDLGNVWRFPYVCYQNGGGAFLIPYVIMAVFGGIPLFYMELAMGQYHRNGCIS 183

  Fly   145 VY-DFSPIMRGIGYGQVLATGIVTTYYATLMALTLRYFVDSFYPTLPWSYCREEWGT-ECLDSGP 207
            :: ...|:.:||||...:....|..||.|:||..|.|.:.||...|||:.|..||.| .|.:
 Frog   184 IWRKICPLFKGIGYAICMIALYVAFYYNTIMAWALYYLIFSFRSELPWTSCLNEWNTGNCTN--- 245

  Fly   208 QEASRATSLAGSGVRTTSAEFYFTNIILR--EKASIDDGIGYPSWSLALALAVAWIVIAGIMFKG 270
              ..:.:|:..|....:.||.::|.::|:  :...:.| :|..||.|.|.|.:.:.|:...::||
 Frog   246 --YFQNSSVGWSNSSISPAEEFYTRLVLQIHKSKGLHD-LGGISWQLTLCLLLIFTVVYFSIWKG 307

  Fly   271 VKSSGKASYFLALFPYVVMLVLLVRALTLPGAFDGVLYFLRPQWHKLLEPQVWYAAVTQVFFSLA 335
            ||:|||..:..|.|||:|:.:||:|..|||||:.|||::|:|.|.|||...||..|..|:||||.
 Frog   308 VKTSGKVVWVTATFPYIVLALLLIRGATLPGAWRGVLFYLQPDWEKLLTTAVWVDAAAQIFFSLG 372

  Fly   336 ICFGNIIMYASYNRFGHNIYRDANIVTTLDTFTSLLSGVIIFGILGNLAYENNTTDIASVV-NGG 399
            ..||.::.:||||:|.:|.|:||.|.:|::..||.:||::||.:||.:| |....|::.|. :.|
 Frog   373 PGFGVLLAFASYNKFHNNCYQDALITSTVNCMTSFMSGLVIFTVLGYMA-EMRNLDVSEVAKDTG 436

  Fly   400 PGLAFISYPDAIAKFKWLP--QLFSVLFFLMLFVLGIGSNVGMASCMSTVIKDQFGHL--KNWTV 460
            |.|.||:|.:|||.   :|  ..|:::|||||..||:.|.......:.|.:.|:|.|:  |...:
 Frog   437 PSLLFITYAEAIAN---MPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHIWGKRREL 498

  Fly   461 VVGIAIVGYFLGLL-YITPGGQFLLNLVDYFGVTFVALVLAIFELVTIAWIYGVKRLCRDVEFMI 524
            .|.:.|...|||.| .:|.||.:::.|.:.:......|.:...|.:.::|.||:.:.||||..|:
 Frog   499 FVFLLISVCFLGALSTLTFGGAYMVKLFEEYATGPAVLTVVFLEAIAVSWFYGINQFCRDVREML 563

  Fly   525 GIKTSLYYRICWAVVTPLLMLTILIYTLVLYEPLKYKDYTYQSGVYVFGWCLSAFGVGQVLFWAI 589
            |.....:::|||..:.||.:|.|:...:.....|:..:|.|.|...|.|:|     :|...|..:
 Frog   564 GFSPGWFWKICWVAICPLFLLFIICSFMSSPPDLRLFNYQYPSWTVVLGYC-----IGTSSFICV 623

  Fly   590 PA 591
            ||
 Frog   624 PA 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1698	NP_001260835.1	SLC6sbd	75..552	CDD:271359	183/486 (38%)
slc6a4	XP_017946918.1	5HT_transport_N	48..91	CDD:367522	10/32 (31%)
		SLC5-6-like_sbd	113..649	CDD:382020	195/528 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010