DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1698 and slc6a13

DIOPT Version :9

Sequence 1:	NP_001260835.1	Gene:	CG1698 / 36006	FlyBaseID:	FBgn0033443	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	XP_002667408.5	Gene:	slc6a13 / 100332592	ZFINID:	ZDB-GENE-170607-2	Length:	621	Species:	Danio rerio

Alignment Length:	584	Identity:	219/584 - (37%)
Similarity:	328/584 - (56%)	Gaps:	18/584 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 KKRDSWNNDIEFLMSCIALSVGLGNVWRFPFTALENGGGAFVIPYLIVLILVGKPVYYLEMLLGQ 136
            |.|..|:|.:||::|.....:|||||||||:...:||||||.|||||.|...|.||::||:.|||
Zfish    28 KDRGQWSNKLEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFLFTCGIPVFFLEISLGQ 92

  Fly   137 FSSRGSVKVY-DFSPIMRGIGYGQVLATGIVTTYYATLMALTLRYFVDSFYPTLPWSYCREEWGT 200
            ::|.|.:..: ..||:..||||...:...::..||..::|..:.|..:||...||||.|...|.|
Zfish    93 YTSEGGITCWRKISPLFEGIGYATQVIVALLNFYYIIVLAWGIFYLSNSFTWNLPWSSCNNTWNT 157

  Fly   201 E-CLDSGPQEASRATSLAGSGVRTTSAEFYFTNIILREKASIDDGIGYPSWSLALALAVAWIVIA 264
            | |::...:..|...|...:.  |:....::...:||..:.|:| ||...|.|.|.|.:||::..
Zfish   158 ESCMEFQRRNDSVDQSYLDNA--TSPVIEFWERRVLRISSGIED-IGTLHWDLVLCLLLAWVLCY 219

  Fly   265 GIMFKGVKSSGKASYFLALFPYVVMLVLLVRALTLPGAFDGVLYFLRPQWHKLLEPQVWYAAVTQ 329
            ..::|||||:||..||.|.||||::|:||:|.:|||||..|:.::|.|...:|.:||||..|.||
Zfish   220 FCIWKGVKSTGKVVYFTATFPYVMLLILLIRGVTLPGASRGIQFYLYPDLGRLADPQVWMDAGTQ 284

  Fly   330 VFFSLAICFGNIIMYASYNRFGHNIYRDANIVTTLDTFTSLLSGVIIFGILGNLAYENNTTDIAS 394
            :|||.|||.|.:....|||::.:|.|||:..:..|::.||.::|..||.|||.::||.| ..|:.
Zfish   285 IFFSYAICLGCLTALGSYNKYNNNCYRDSLALCFLNSGTSFVAGFAIFSILGFMSYEQN-VPISE 348

  Fly   395 VVNGGPGLAFISYPDAIAKFKWLPQLFSVLFFLMLFVLGIGSNVGMASCMSTVIKD---QFGHLK 456
            |...|||||||:||.|::.....| |::..||:|:.:||:.|.......:.|.:.|   .|...|
Zfish   349 VAESGPGLAFIAYPRAVSMMPISP-LWACFFFIMIVLLGLDSQFVCVESLVTAMVDMYPSFFRRK 412

  Fly   457 N--WTVVVGIAIVGYFLGLLYITPGGQFLLNLVDYFGVTFVALV-LAIFELVTIAWIYGVKRLCR 518
            |  ..:::.:|||.:.:||:.:|.||.::..|.||:..:.:.|: :||||.|.||||||..|...
Zfish   413 NRRELLILVVAIVSFLVGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFETVCIAWIYGANRFYD 477

  Fly   519 DVEFMIGIKTSLYYRICWAVVTPLLMLTILIYTLVLYEPLKY-KDYTYQSGVYVFGWCLSAFGVG 582
            ::|.|||.:...|.:.||...||........::|:.|.|||| .:|.|....|..||.|:...:.
Zfish   478 NIEDMIGYRPGPYIKYCWLFFTPATCFGTFAFSLIKYTPLKYNNEYVYPWWGYALGWMLALSSMI 542

  Fly   583 QVLFWAIPAVRKQPSHLGLWARIRKAFEPLPNWGPSDPQTLKRYQLFVQEGNANALFRRSSIWH 646
            .|..|.|  .|...:...|..|::....|.|:...|..:..|...:|..:|  ::|.:.|:..|
Zfish   543 CVPLWVI--YRMGTTKGSLMERVQFLIRPSPDLPKSRREQEKLQAVFSADG--DSLHQHSTHTH 602

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1698	NP_001260835.1	SLC6sbd	75..552	CDD:271359	190/484 (39%)
slc6a13	XP_002667408.5	SLC6sbd-TauT-like	30..569	CDD:271387	209/545 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820