DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1698 and si:ch211-132b12.3

DIOPT Version :9

Sequence 1:	NP_001260835.1	Gene:	CG1698 / 36006	FlyBaseID:	FBgn0033443	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_001076419.1	Gene:	si:ch211-132b12.3 / 100002232	ZFINID:	ZDB-GENE-050419-161	Length:	577	Species:	Danio rerio

Alignment Length:	590	Identity:	205/590 - (34%)
Similarity:	322/590 - (54%)	Gaps:	38/590 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 KKRDSWNNDIEFLMSCIALSVGLGNVWRFPFTALENGGGAFVIPYLIVLILVGKPVYYLEMLLGQ 136
            ::|..|....|||::.....||:|||||||:....||||.|:||||:.::..|.|::.||.::||
Zfish     9 EERGFWGRKAEFLLAVAGNVVGVGNVWRFPYLCYRNGGGVFLIPYLVFVMTCGVPLFLLETVMGQ 73

  Fly   137 FSSRGSVKVYD-FSPIMRGIGYGQVLATGIVTTYYATLMALTLRYFVDSFYPTLPWSYCREEWGT 200
            |:..|.:..:. ..|:.:|:||...|.......|:..::|..|.|.:.||...|||:.|...|.|
Zfish    74 FTHEGGITCWHLLCPLAQGVGYAGQLIELYSCMYFTIILAWALFYLIFSFSSQLPWASCDNIWNT 138

  Fly   201 E-C--LDSGPQEASRATSLAGSGVRTTSAEFYFTNIILREKASIDDGIGYPSWSLALALAVAWIV 262
            : |  |.:|....:|.|.:..    |::|..::...:|.....|:: ||..:|.:||.|.|.||:
Zfish   139 DNCVNLAAGNLTFNRTTQINS----TSAATEFWERRVLSLSGGIEE-IGKINWEIALCLFVMWII 198

  Fly   263 IAGIMFKGVKSSGKASYFLALFPYVVMLVLLVRALTLPGAFDGVLYFLRPQWHKLLEPQVWYAAV 327
            ....::|||||:||..||.|.||||::||||:|.||||||..||:::|.|:...|.:||||..|.
Zfish   199 CYFCIWKGVKSTGKVVYFTATFPYVMLLVLLIRGLTLPGALQGVVFYLYPEPAHLADPQVWMEAG 263

  Fly   328 TQVFFSLAICFGNIIMYASYNRFGHNIYRDANIVTTLDTFTSLLSGVIIFGILGNLAYENNTTDI 392
            ||||||.::|.|.:|...|||::.:|.|||:..:..|::.||.::|..:|.:||.:|:... ..:
Zfish   264 TQVFFSYSLCSGILIALGSYNQYSNNCYRDSFWLCLLNSGTSFVAGFAVFSVLGFMAHVQG-VPV 327

  Fly   393 ASVVNGGPGLAFISYPDAIAKFKWLPQLFSVLFFLMLFVLGIGSNVGMASCMSTVIKDQFGHL-- 455
            ..|...|||||||:||.|:|...: |||::|.||:|:.:||:.|......|:.|.:.|.|..:
Zfish   328 EEVAESGPGLAFIAYPQAVAMMPF-PQLWAVCFFIMIILLGLDSQFVAMECVVTSVTDLFPEVLR 391

  Fly   456 ---KNWTVVVGIAIVGYFLGLLYITPGGQFLLNLVDYF---GVTFVALVLAIFELVTIAWIYGVK 514
               :....|:.:.:..:|..|:.:|.||.::..|.|.:   |..|  |.|::||.:||.||:|.:
Zfish   392 RAGRRELFVLLLCLTCFFGQLIMVTEGGMYVFQLFDNYASNGACF--LFLSVFESLTIGWIFGAE 454

  Fly   515 RLCRDVEFMIGIKTSLYYRICWAVVTPLLMLTILIYTLVLYEPLKY-KDYTYQSGVYVFGWCLSA 578
            ::...::.|...:.:.::.:||..:|||:.||..:|::|.|.||.| :.|.|....:|.||.|:.
Zfish   455 KMFDIIKDMTESRPNYWFMLCWKYLTPLVSLTSFVYSMVRYTPLTYNRWYVYPDWAHVLGWLLAL 519

  Fly   579 FGVGQVLFWAIPAVRKQPSHLGLWARIRKAFEPLPNWG----PSDPQTLKRYQLFVQEGNANALF 639
            ..:..|..||          ||.....:.:.:  ..||    |.....|...|:..|......|.
Zfish   520 SSILLVPGWA----------LGQMCTGKGSLK--QRWGHLCSPDTNLMLSSIQIQEQTAEMEDLV 572

  Fly   640 RRSSI 644
            |.|:|
Zfish   573 RSSTI 577

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1698	NP_001260835.1	SLC6sbd	75..552	CDD:271359	178/488 (36%)
si:ch211-132b12.3	NP_001076419.1	SLC6sbd-TauT-like	11..550	CDD:271387	197/559 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820