DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1688 and KCNK6

DIOPT Version :9

Sequence 1:	NP_610516.1	Gene:	CG1688 / 36005	FlyBaseID:	FBgn0027589	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_004814.1	Gene:	KCNK6 / 9424	HGNCID:	6281	Length:	313	Species:	Homo sapiens

Alignment Length:	180	Identity:	54/180 - (30%)
Similarity:	79/180 - (43%)	Gaps:	35/180 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 GLVLLVIGYSVLGGLLFPLLEAPQDISKSAAIAKSREDCL-RELWIITEKLNVLYERNWTMLVHE 141
            |.:.....|.|||.||...||.|.:....|.:...|...| |...:....|:...||   :|...
Human     9 GALAAYAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFVER---VLAAG 70

  Fly   142 QLRRFEGSIVAATRQGSAGSSGGGGAGLFHEGSASALGHFGYDAGDSQSWSFSEALLYSVTVITT 206
            :|    |.:|.|...|||.:|                         ..:|.|:.||.::.|:|||
Human    71 RL----GRVVLANASGSANAS-------------------------DPAWDFASALFFASTLITT 106

  Fly   207 IGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLGALLADGLQCTYVRL 256
            :|:|..||.|.|||..:|.:||:|||..::.|::....|:  |..|:|.|
Human   107 VGYGYTTPLTDAGKAFSIAFALLGVPTTMLLLTASAQRLS--LLLTHVPL 154

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168	24/55 (44%)
CG1688	NP_610516.1	Ion_trans_2	822..896	CDD:285168
KCNK6	NP_004814.1	Ion_trans_2	<91..146	CDD:285168	23/54 (43%)
		Ion_trans_2	180..256	CDD:285168
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	288..313
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	57	1.000	Domainoid score	I10857
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	121	1.000	Inparanoid score	I4753
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.860