Protein Alignment CG1688 and KCNK17

DIOPT Version :10

• Sequence 1: NP_610516.1
• Gene: CG1688 / 36005
• FlyBaseID: FBgn0027589
• Length: 918
• Species: Drosophila melanogaster
• Sequence 2: NP_113648.2
• Gene: KCNK17 / 89822
• HGNCID: 14465
• Length: 332
• Species: Homo sapiens
• Alignment Length: 199
• Identity: 58/199 - (29%)
• Similarity: 89/199 - (44%)
• Gaps: 52/199 - (26%)

  Fly    56 AKPRSSLRRCCGHLLKLLFSTPGLVLLV---IGYSVLGGLLFPLLE--APQDISKSAAIAKSRED 115
            |.|...:|.|         :.|..|||:   :.|..||..:|..||  |.||.|:|..
Human     8 AAPEGRVRGC---------AVPSTVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQ------- 56

  Fly   116 CLRELWIITEKLNVLYERNWTMLVHEQLRRFEGSIVAATRQGSAGSSGGGGAGLFHEGSASALGH 180
              |:.|.:.:        |:|.|....|......:|.|.:.|::..|           :.:::|.
Human    57 --RDKWELLQ--------NFTCLDRPALDSLIRDVVQAYKNGASLLS-----------NTTSMGR 100

  Fly   181 FGYDAGDSQSWSFSEALLYSVTVITTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLGALL 245
                      |....:..:||:.|||||:|:|:|.|.|.:|..||:||||:||.|:.|:.||.|:
Human   101 ----------WELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVGIPLNLVVLNRLGHLM 155

  Fly   246 ADGL 249
            ..|:
Human   156 QQGV 159

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	177..247	CDD:462301	28/69 (41%)
		Ion_trans_2	822..896	CDD:462301
KCNK17	NP_113648.2	Ion_trans_2	81..157	CDD:462301	32/96 (33%)
		Selectivity filter 1. /evidence=ECO:0000250|UniProtKB:P57789	116..121		3/4 (75%)
		Ion_trans_2	<206..268	CDD:462301
		Selectivity filter 2. /evidence=ECO:0000250|UniProtKB:P57789	221..226
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..312