Protein Alignment CG1688 and KCNK5

DIOPT Version :10

• Sequence 1: NP_610516.1
• Gene: CG1688 / 36005
• FlyBaseID: FBgn0027589
• Length: 918
• Species: Drosophila melanogaster
• Sequence 2: NP_003731.1
• Gene: KCNK5 / 8645
• HGNCID: 6280
• Length: 499
• Species: Homo sapiens
• Alignment Length: 168
• Identity: 50/168 - (29%)
• Similarity: 80/168 - (47%)
• Gaps: 41/168 - (24%)

  Fly    77 PGLVLLVIGYSVLGGLLFPLLEAP--QDISKSAAIAKSREDCLRELWIITEKLNVLYERNWTMLV 139
            |.|...:|.|..:|..:|.:||.|  ::..|:               ..|:||::|.|  :..|.
Human     6 PLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKN---------------YYTQKLHLLKE--FPCLG 53

  Fly   140 HEQLRRFEGSIVAATRQGSAGSSGGGGAGLFHEGSASALGHFGYDAGDSQSWSFSEALLYSVTVI 204
            .|.|.:....:..|..||.|.:    |...|:                  :|::..|::::.|||
Human    54 QEGLDKILEVVSDAAGQGVAIT----GNQTFN------------------NWNWPNAMIFAATVI 96

  Fly   205 TTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLG 242
            ||||:|::.|:|.||:|..:||.|.||||.|..:|:||
Human    97 TTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTWISALG 134

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	177..247	CDD:462301	26/66 (39%)
		Ion_trans_2	822..896	CDD:462301
KCNK5	NP_003731.1	Ion_trans_2	<83..137	CDD:462301	26/52 (50%)
		Selectivity filter 1. /evidence=ECO:0000250|UniProtKB:P57789	98..103		3/4 (75%)
		Ion_trans_2	171..243	CDD:462301
		Selectivity filter 2. /evidence=ECO:0000250|UniProtKB:P57789	203..208
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	312..335
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	360..388
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	428..499