Protein Alignment CG1688 and Kcnk10

DIOPT Version :10

• Sequence 1: NP_610516.1
• Gene: CG1688 / 36005
• FlyBaseID: FBgn0027589
• Length: 918
• Species: Drosophila melanogaster
• Sequence 2: NP_075584.1
• Gene: Kcnk10 / 65272
• RGDID: 619732
• Length: 538
• Species: Rattus norvegicus
• Alignment Length: 165
• Identity: 46/165 - (27%)
• Similarity: 75/165 - (45%)
• Gaps: 37/165 - (22%)

  Fly    79 LVLLVIGYSVLGGLLFPLLEAPQDISKSAAIAKSREDCLRE-LWIITEKLNVLYERNWTMLVHEQ 142
            :.::|:.|.|.|||:|..||.|.:.|:...||..:.:.||: :.:..::|.       |::.|
  Rat    75 IFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHICVSPQELE-------TLIQH-- 130

  Fly   143 LRRFEGSIVAATRQGSAGSSGGGGAGLFHEGSASALGHFGYDAGDSQSWSFSEALLYSVTVITTI 207
                      |....:||.|..|.:                 :..|..|....|..::.||||||
  Rat   131 ----------ALDADNAGVSPVGNS-----------------SNSSSHWDLGSAFFFAGTVITTI 168

  Fly   208 GHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLG 242
            |:|::.|.|..||:..|.||:.|:||....|:.:|
  Rat   169 GYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIG 203

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	177..247	CDD:462301	23/66 (35%)
		Ion_trans_2	822..896	CDD:462301
Kcnk10	NP_075584.1	Ion_trans_2	<150..206	CDD:462301	22/54 (41%)
		Selectivity filter 1. /evidence=ECO:0000250|UniProtKB:P57789	167..172		3/4 (75%)
		Ion_trans_2	244..323	CDD:462301
		Selectivity filter 2. /evidence=ECO:0000250|UniProtKB:P57789	276..281
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	412..444