DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1688 and kcnk5a

DIOPT Version :9

Sequence 1:	NP_610516.1	Gene:	CG1688 / 36005	FlyBaseID:	FBgn0027589	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_001032478.1	Gene:	kcnk5a / 570159	ZFINID:	ZDB-GENE-051113-112	Length:	513	Species:	Danio rerio

Alignment Length:	170	Identity:	45/170 - (26%)
Similarity:	76/170 - (44%)	Gaps:	45/170 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 PGLVLLVIGYSVLGGLLFPLLEAPQDISKSAAIAKSR---EDCLRELWIITE-KLNVLYERNWTM 137
            |.|...:|.|..:|..:|.::|.|   :...|:.|.|   |..|::...:|: .|:.:.|
Zfish     6 PLLTSAIIFYLSIGAAIFQVIEEP---NWEIAVRKYRADKESILKQYPCLTKADLDYILE----- 62

  Fly   138 LVHEQLRRFEGSIVAATRQGSAGSSGGGGAGLFHEGSASALGHFGYDAGDSQSWSFSEALLYSVT 202
                        :|          |...|.|:...|..:           ..:|::..|::::.|
Zfish    63 ------------VV----------SDAAGQGITITGDKT-----------FNNWNWPNAVIFAAT 94

  Fly   203 VITTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLG 242
            ||||||:|::.|:|.:|::..|||.|.||||....:|.||
Zfish    95 VITTIGYGNIAPKTPSGRVFCIFYGLFGVPLCFTWISELG 134

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168	24/52 (46%)
CG1688	NP_610516.1	Ion_trans_2	822..896	CDD:285168
kcnk5a	NP_001032478.1	Ion_trans_2	<81..137	CDD:285168	24/54 (44%)
kcnk5a	NP_001032478.1	Ion_trans_2	171..243	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.910