Protein Alignment CG1688 and kcnb2b

DIOPT Version :10

• Sequence 1: NP_610516.1
• Gene: CG1688 / 36005
• FlyBaseID: FBgn0027589
• Length: 918
• Species: Drosophila melanogaster
• Sequence 2: XP_695259.4
• Gene: kcnb2b / 566883
• ZFINID: ZDB-GENE-091113-38
• Length: 831
• Species: Danio rerio
• Alignment Length: 704
• Identity: 134/704 - (19%)
• Similarity: 231/704 - (32%)
• Gaps: 241/704 - (34%)

  Fly    54 LTAKPRSSLRRCCGHLLKLLFSTPGLVLLVIGYSVLGGLLFPLLEAPQDISK---SAAIAKSRED 115
            |..||.||:......::.:||    :||..:..|:   ...|.|:...:..:   :..:|.....
Zfish   183 LLEKPSSSVAAKILAIISILF----IVLSTVALSL---NTLPELQVTDEFGQANDNPQLAHVEAV 240

  Fly   116 CLRELWIITE-----------------KLNV--------------LYERNWTMLVHEQLRR---- 145
            |:  .|...|                 .|||              |.|.|.::|..:.:||
Zfish   241 CI--AWFTMEYLLRFLSSPNKWKFFKGPLNVIDLLAILPYYVTIFLTESNKSVLQFQNVRRVVQI 303

  Fly   146 FEGSIVAATRQGSAGSSGGGGAGLFHEGSASALG-----------------HFGYDAGDSQSWSF 193
            |....:....:.:..|:|....|.....|.:.||                 .|.....|:..::.
Zfish   304 FRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDATKFTS 368

  Fly   194 SEALLYSVTV-ITTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLGALLADGLQCTYVRLC 257
            ..|..:..|: :||:|:|.:.|:|..||:......:.||.::.:.:    .::.:.....|
Zfish   369 IPASFWWATITMTTVGYGDIYPQTLLGKIVGGLCCIAGVLVIALPI----PIIVNNFSEFY---- 425

  Fly   258 CQLQRHQE---HRRKSTPGTSTPSASSAANSR--------------EKDTDKR-SKRRMANCKGC 304
             :.|:.||   .||::........:..:.|.:              ||..||| :...::..:..
Zfish   426 -KEQKRQEKAIKRREALERAKRNGSIVSMNLKDAFARSMELMDVTVEKSDDKRLTDNHLSPSRWG 489

  Fly   305 QYDAANSETSLNDCLEYGQKGKLPPDKKEGDACQLLRNLNPQQHFYQQQQQQPQQPDVMLMTTTS 369
            .....:|:|||...           |||       ..|...|::.:....|.           .:
Zfish   490 IPQRTSSDTSLRSF-----------DKK-------FPNSGSQEYVHMPSPQH-----------LN 525

  Fly   370 GSALLKYAPQQQQLQQQQQLST--ATLPR--QHHQMQLQQQQQQLQQNFVAVPSSMLRMP--LTV 428
            ...|.:...|..:.|....|||  :|.|.  ..|:::|:.::         ||:::.:.|  .|:
Zfish   526 AQNLEEMYNQMTKTQSFSDLSTSNSTQPAVVSKHEVELEMKE---------VPTAVKQQPKERTI 581

  Fly   429 PP-------NCYAPATATIYFPFGHAPSAPGSPAH-----NQAHPTQNPNGNALGNTTLG----- 476
            ..       :.:|..||    .||....|. :|:|     .|..|..:|..: ||..|..
Zfish   582 TDVRSISSVDSFASCTA----EFGQGEKAT-TPSHTAEQFQQRLPKVSPQLH-LGQLTPSDLSPE 640

  Fly   477 -SQPLVKYHTIHL--------QPASGKHRVLASGLQDATAVNLVTASEASTSTLEAITLPPPPAY 532
             :..:|...|..|        ....|.:.:.|.||:    ||.:       .|.|...|.||
Zfish   641 ENSGIVNRDTDDLNEFVENIRSSIRGTNPIKAKGLK----VNFI-------ETPEDAPLTPP--- 691

  Fly   533 QTASVHAVRRAKFVAKPLPQEI-NALMDC----GTGSPDLSGRHDLLPPPHSGSPATGTAASP-- 590
            .|:|              ||:| |:|::.    |..||..|....:     .|:...|...||
Zfish   692 NTSS--------------PQDINNSLLEDDSPEGECSPLCSDSETV-----GGNSMEGLVLSPKK 737

  Fly   591 ----------------------------LLTYTAAATSPQLSA-----GIKGGS 611
                                        :...:||.:||:|:|     .|.||:
Zfish   738 LPGRCHPGETVLLLGNLEEQEYLDEQNQMEVASAAISSPKLAAQNCSQNIIGGN 791

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	177..247	CDD:462301	16/87 (18%)
		Ion_trans_2	822..896	CDD:462301
kcnb2b	XP_695259.4	BTB_POZ_KCNB2	19..145	CDD:349719
		Ion_trans	193..429	CDD:459842	42/253 (17%)
		Kv2channel	480..706	CDD:397541	59/297 (20%)