Protein Alignment CG1688 and Ork1

DIOPT Version :10

• Sequence 1: NP_610516.1
• Gene: CG1688 / 36005
• FlyBaseID: FBgn0027589
• Length: 918
• Species: Drosophila melanogaster
• Sequence 2: XP_061504627.1
• Gene: Ork1 / 5667673
• VectorBaseID: AGAMI1_013932
• Length: 891
• Species: Anopheles gambiae
• Alignment Length: 802
• Identity: 146/802 - (18%)
• Similarity: 247/802 - (30%)
• Gaps: 280/802 - (34%)

  Fly   191 WSFSEALLYSVTVITTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLGALLADGLQCTYVR 255
            |.|..:..::..:.:|:|:|:::|....|::..|||||:|:|:.....:.:|...|.|    :||
Mosquito    91 WDFYHSFYFAFIICSTVGYGNISPHNTFGRIFLIFYALIGLPVNGFFFAYVGEFWARG----FVR 151

  Fly   256 LCCQLQRHQEHRRKSTPGTS-----------------------TPS------------------- 278
            |   .:|::.::..:..|.:                       .|:
Mosquito   152 L---YRRYKAYKLSANAGYAPRRISFIGQIVLYLIPGVIVFIFAPACVFTYFEQWPYDVSVYYSF 213

  Fly   279 -----------ASSAANSRE--------------------------------------KDTDKRS 294
                       |:|...|::                                      |...:..
Mosquito   214 VTLTTIGFGDYAASFQPSQQHEFGSLFTVYKIFIIFWFFAGIGYIFMILGFIAKGISHKKIQQLE 278

  Fly   295 KRRMANCKGCQYDAANSETS--------LND--CLEYGQKGKLPPD------KKEGDACQLLRNL 343
            |...:|.|..|:...|..|.        ||:  .|::....:.|.|      |....:|
Mosquito   279 KLVASNLKETQHRVWNGVTKDISYLRRILNEVYMLKFKPVYEEPSDRWLSLSKSRSSSC------ 337

  Fly   344 NPQQHFYQQQQQQPQQPDVMLMTTTSGSALLKYAPQQ-QQLQQQQQLSTATLPRQHHQ----MQL 403
             |:...|    :.|:||.:......|.|||:..|.:. ......::||...|.|.:.:    :|.
Mosquito   338 -PELSMY----RPPEQPTIRRKRANSESALVFAATRPVDGGSLVRRLSDTDLNRINREKTFGVQA 397

  Fly   404 QQQQQQLQQNFVAV-----------PSSMLRMPLTVPPNCYAPA--TATIYFPFGHAPSAPGSPA 455
            ..|..:|....|..           .|.:.|..|....||::.:  .|:.....|.:.|.....|
Mosquito   398 LVQPAELLARVVTALGNITANQDDNQSFLERASLNAGVNCFSDSQILASERTWSGWSMSGSDKSA 462

  Fly   456 HNQAHPTQNPNGNALGNTTLGSQPLVKYHTIHLQPASGKHRVLASG----LQDATAV-------- 508
            :..| |...|.    ..:.:|..|       ||..........:.|    :|:...|
Mosquito   463 YLTA-PPMRPR----AASDIGVPP-------HLSSQDANEWTWSGGDNSQIQEILQVRQKVKQKD 515

  Fly   509 NLVTASEASTSTLE-AITLPPPPAYQTASVHAV------------RRAKFVAKPLPQEINA---- 556
            ||:.|:.::....: ::|:..||..:.:...||            :|:|.:|   |.:|..
Mosquito   516 NLLRAALSNNVNFDSSLTINMPPTGRESKASAVNRSVLQRLNPFRKRSKQLA---PADIETAPGL 577

  Fly   557 ---LMDCGTG-------------SPDLSGRHDLLPPP---------------------------- 577
               |...|.|             |....||..:|..|
Mosquito   578 DSYLAATGKGRSSMFNLPTSSYLSATSRGRGSILSMPPQDEHLLETTTIGDLLRALELMHTDTVT 642

  Fly   578 -----HSGSPATGTAASPLLTYTAAATSPQLSAGIKGGSGPAP---TAGAPMLVSGAGRGAAALT 634
                 |.||..||...:..|.:.|.....|..|   ||:...|   |...|.:.:|..|
Mosquito   643 AGAGQHRGSVGTGEPQAATLHHRAGRHQSQPFA---GGASNLPSLLTLFTPPIEAGGSR------ 698

  Fly   635 DNGFMAAGVCGMGAA-AAPLPVTSMGAATTTASSAASTLSALLSANSTGNVDIMEDEDEQERERL 698
             .|.:...:...|:| :||..:.......|...|.::|:|...:...:..:.|:....:..|.|.
Mosquito   699 -RGSLKPPLGRTGSADSAPSVLRRPSFRPTNPPSYSATVSGSPAGGGSPTLGIIGPSPKPIRRRF 762

  Fly   699 S-----------NCPHGTPSRVPLIASPLSVPQDSGENTTRNTAFNRHTLQPLSRKTLLLTRRCH 752
            |           :||     |.|  |.|...|:..|.....:::.:.|.|     .|..|.||..
Mosquito   763 SVRPSNLAYPPGHCP-----RPP--AGPTGGPELPGSPHISSSSQSLHNL-----PTTTLQRRLS 815

  Fly   753 -------RHASGTLYDSTANNT 767
                   .|.|..|...:|..|
Mosquito   816 SRPSPLATHQSSHLTVPSAGGT 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	177..247	CDD:462301	15/55 (27%)
		Ion_trans_2	822..896	CDD:462301
Ork1	XP_061504627.1	None