DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1688 and kcnk10b

DIOPT Version :9

Sequence 1:	NP_610516.1	Gene:	CG1688 / 36005	FlyBaseID:	FBgn0027589	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	XP_005169840.1	Gene:	kcnk10b / 565629	ZFINID:	ZDB-GENE-050420-31	Length:	575	Species:	Danio rerio

Alignment Length:	279	Identity:	69/279 - (24%)
Similarity:	109/279 - (39%)	Gaps:	77/279 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VEQAIKAKQ-PQPSQL---DC-----SIDDETDATEFGGLGGVGGAGCGSEMGAKTTASLTAKPR 59
            |:.::.|.| |...:|   .|     ||...:.:...|...|..|:...|.|..||..:
Zfish    41 VQASVSAMQNPMGCELKNGHCLLPRLSISSRSASVLTGMDSGADGSALHSVMKWKTVLA------ 99

  Fly    60 SSLRRCCGHLLKLLFSTPGLVLLVIGYSVLGGLLFPLLEAP-QDISKSAAIAKSREDCLRELWII 123
                               :.::|:.|.|.|||.|..||.| :.|.|.:               |
Zfish   100 -------------------VFVVVLSYLVCGGLAFQALEQPFESIQKDS---------------I 130

  Fly   124 TEKLNVLYERNWTMLVHEQLRRFEGSIVAATRQGSAGSSGGGGAGLFHEGSASALGHFGYDAGDS 188
            |:|.....::| ..:.|..|   |..|..|....|.|              .|.:|...|   :|
Zfish   131 TQKKAQFLQKN-PCVSHADL---EALIKHAVEAVSTG--------------VSPIGDASY---NS 174

  Fly   189 QSWSFSEALLYSVTVITTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLGALLADGLQCTY 253
            ..|....|..::.|||||||:|::.|.|..||:..|.||:.|:||....|:.:|    |.|...:
Zfish   175 SQWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGVG----DQLGTMF 235

  Fly   254 VRLCCQLQR--HQEHRRKS 270
            ::...::::  .|:|::.|
Zfish   236 MKSILRVEKVFRQKHKQIS 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168	22/55 (40%)
CG1688	NP_610516.1	Ion_trans_2	822..896	CDD:285168
kcnk10b	XP_005169840.1	Ion_trans_2	172..231	CDD:285168	25/65 (38%)
kcnk10b	XP_005169840.1	Ion_trans_2	271..350	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	69	1.000	Domainoid score	I9562
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.910