DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1688 and kcnk2a

DIOPT Version :9

Sequence 1:	NP_610516.1	Gene:	CG1688 / 36005	FlyBaseID:	FBgn0027589	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	XP_021323122.1	Gene:	kcnk2a / 559728	ZFINID:	ZDB-GENE-061226-2	Length:	426	Species:	Danio rerio

Alignment Length:	175	Identity:	49/175 - (28%)
Similarity:	78/175 - (44%)	Gaps:	39/175 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 LVLLVIGYSVLGGLLFPLLEAPQDISKSAAIAKSREDCLRELWIITEKLNVLYERNWTMLVHEQL 143
            :.|||:.|.::|..:|..||.|             |:.|::..||.||::.|...  |.:...:|
Zfish    63 IFLLVVLYLIIGATVFKALEQP-------------EEGLQKYRIIQEKIDFLSMH--TCVNTSEL 112

  Fly   144 RRFEGSIVAATRQGSAGSSGGGGAGLFHEGSASALGHFGYDAGDSQSWSFSEALLYSVTVITTIG 208
            ......:|.|.|.|...|                    |:.:.:|..|..|.:..::.|||||||
Zfish   113 EDLVKQVVLAIRAGVNPS--------------------GHPSNESSMWDLSSSFFFAGTVITTIG 157

  Fly   209 HGSLTPRTAAGKLATIFYALVGVPLMLMCLS----SLGALLADGL 249
            .|:::|.|..|::..|.|||:|:||....|:    .||.:...|:
Zfish   158 FGNVSPHTEGGRIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGI 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168	23/59 (39%)
CG1688	NP_610516.1	Ion_trans_2	822..896	CDD:285168
kcnk2a	XP_021323122.1	Ion_trans_2	<140..194	CDD:311712	21/53 (40%)
kcnk2a	XP_021323122.1	Ion_trans_2	232..310	CDD:311712
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	69	1.000	Domainoid score	I9562
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.910