DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1688 and KCNS3

DIOPT Version :10

Sequence 1:NP_610516.1 Gene:CG1688 / 36005 FlyBaseID:FBgn0027589 Length:918 Species:Drosophila melanogaster
Sequence 2:NP_002243.3 Gene:KCNS3 / 3790 HGNCID:6302 Length:491 Species:Homo sapiens


Alignment Length:156 Identity:35/156 - (22%)
Similarity:66/156 - (42%) Gaps:36/156 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   760 YDSTANNTETSDDEEYMQHGSEQFVLK--------KLRYHCDGKDCREAEDSEEEDEKADGRQVP 816
            |.:.|.:|:..:.|:....|....:|:        ||..|..|.....|.......|        
Human   267 YATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHE-------- 323

  Fly   817 ISLVLLILASYICVGTVIFALW-------ENWSLVDGAYFCF----VTLSTIGYGDFVPARSFNG 870
            :.|:||.|:    ||..||::.       ::.|.:.....|:    ::::|:||||..|. :..|
Human   324 VGLLLLFLS----VGISIFSVLIYSVEKDDHTSSLTSIPICWWWATISMTTVGYGDTHPV-TLAG 383

  Fly   871 PELQLYACCAYLLLGLVLVAMSFSIL 896
             :|....|   ::.|:::||:..:|:
Human   384 -KLIASTC---IICGILVVALPITII 405

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1688NP_610516.1 Ion_trans_2 177..247 CDD:462301
Ion_trans_2 822..896 CDD:462301 20/84 (24%)
KCNS3NP_002243.3 BTB_POZ_KCNS3 15..122 CDD:349735
Ion_trans 184..417 CDD:459842 35/156 (22%)
Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142 370..375 3/4 (75%)
Blue background indicates that the domain is not in the aligned region.

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