Protein Alignment CG1688 and KCNC4

DIOPT Version :10

• Sequence 1: NP_610516.1
• Gene: CG1688 / 36005
• FlyBaseID: FBgn0027589
• Length: 918
• Species: Drosophila melanogaster
• Sequence 2: XP_024302558.1
• Gene: KCNC4 / 3749
• HGNCID: 6236
• Length: 661
• Species: Homo sapiens
• Alignment Length: 310
• Identity: 56/310 - (18%)
• Similarity: 101/310 - (32%)
• Gaps: 100/310 - (32%)

  Fly   199 YSVTVITTIGHGSLTPRTAAGKLATIFYALVGVPLMLM----CLSSLGALLADGLQCTYVRLCCQ 259
            ::|..:||:|:|.:.|:|.:|.|.....||.||..:.|    .:::.|         .|..|...
Human   429 WAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFG---------MYYSLAMA 484

  Fly   260 LQRHQEHRRKSTPGTSTPSASSAANSREKDTDKRSKRRMANCKGCQYDAANSETSLNDCLEYGQK 324
            .|:..:.|:|..|..:  ...|....:.::|..|             |:..|:||
Human   485 KQKLPKKRKKHVPRPA--QLESPMYCKSEETSPR-------------DSTCSDTS---------- 524

  Fly   325 GKLPPDKKEGDACQLLRNLNPQQHFYQQQQQQPQQPDV-MLMTTTSGSALLKYAPQQQQLQQQQQ 388
               ||.::||             ...:::....|..|. .:::...|:.|            .|.
Human   525 ---PPAREEG-------------MIERKRADSKQNGDANAVLSDEEGAGL------------TQP 561

  Fly   389 LSTATLPRQHHQMQLQQQQQQLQQNFVAVPSSMLRMPLTVPPNCYAPATATIYFPFGHAPSAPGS 453
            |:::..|.:...::....:.:.::                       |.|......|....|.||
Human   562 LASSPTPEERRALRRSTTRDRNKK-----------------------AAACFLLSTGDYACADGS 603

  Fly   454 PAHNQAHPTQNPN-----GNALGNTTLGSQ-----PLVKYHTIHLQPASG 493
            ............|     |.:||.:.|.|:     ||.|:......|.:|
Human   604 VRKGCGKSRSLNNIVGAAGTSLGLSPLASRYSLPYPLKKFLLTPFHPLTG 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	177..247	CDD:462301	15/51 (29%)
		Ion_trans_2	822..896	CDD:462301
KCNC4	XP_024302558.1	Potassium_chann	1..29	CDD:431870
		BTB_KCNC2_4	35..158	CDD:349722
		Ion_trans	225..483	CDD:459842	17/62 (27%)