Protein Alignment CG1688 and twk-48

DIOPT Version :9

• Sequence 1: NP_610516.1
• Gene: CG1688 / 36005
• FlyBaseID: FBgn0027589
• Length: 918
• Species: Drosophila melanogaster
• Sequence 2: NP_001022681.1
• Gene: twk-48 / 3565640
• WormBaseID: WBGene00010784
• Length: 372
• Species: Caenorhabditis elegans
• Alignment Length: 865
• Identity: 135/865 - (15%)
• Similarity: 215/865 - (24%)
• Gaps: 507/865 - (58%)

  Fly    59 RSSLRRCCGHLLKLL---FSTPGLVLLVIGYSVLGGLLFPLLEAPQDISKSAAIAKSREDCLREL 120
            ||.:.|....:.|::   ||..||..||:||::||.::|..:|.|.:......:..:||..:..:
 Worm     7 RSKVTRVVNLVKKIIAFFFSHIGLCALVVGYALLGAVIFKAVEGPHEAEIQELVKSAREKAVDVV 71

  Fly   121 WIITEKLNVLYERNWTMLVHEQLRRFEGSIVAATRQGSAGSSGGGGAGLFHEGSASALGHFGYDA 185
            |..|.::|.|..:.|...|.::::||:...:.:.|:                      |:.|.:.
 Worm    72 WNATFRVNRLDSKQWKKTVLDEVKRFKTVCMLSIRK----------------------GYDGKEY 114

  Fly   186 GDSQSWSFSEALLYSVTVITTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLGALLADGLQ 250
            |....|:|:.|.|||:|||||||:|:...:|..||..|:.||::|:||||:.|:::|.::|
 Worm   115 GKQAQWTFTGAFLYSLTVITTIGYGNTAAKTYIGKTLTMLYAIIGIPLMLLFLTNIGDVMA---- 175

  Fly   251 CTYVRLCCQLQRHQEHRRKSTPGTSTPSASSAANSREKDTDKRSKRRMANCKGCQYDAANSETSL 315
                                                                             
 Worm   176 ----------------------------------------------------------------- 175

  Fly   316 NDCLEYGQKGKLPPDKKEGDACQLLRNLNPQQHFYQQQQQQPQQPDVMLMTTTSGSALLKYAPQQ 380
                                  ::.|.|..|                        |..||:.
 Worm   176 ----------------------KIFRFLYAQ------------------------SIRLKFR--- 191

  Fly   381 QQLQQQQQLSTATLPRQHHQMQLQQQQQQLQQNFVAVPSSMLRMPLTVPPNCYAPATATIYFPFG 445
                                                                             
 Worm   192 ----------------------------------------------------------------- 191

  Fly   446 HAPSAPGSPAHNQAHPTQNPNGNALGNTTLGSQPLVKYHTIHLQPASGKHRVLASGLQDATAVNL 510
                                              |:.:|         |.|..|.
 Worm   192 ----------------------------------LILWH---------KKRKAAK---------- 203

  Fly   511 VTASEASTSTLEAITLPPPPAYQTASVHAVRRAKFVAKPLPQEINALMDCGTGSPDLSGRHDLLP 575
                                         :|||.
 Worm   204 -----------------------------IRRAN------------------------------- 208

  Fly   576 PPHSGSPATGTAASPLLTYTAAATSPQLSAGIKGGSGPAPTAGAPMLVSGAGRGAAALTDNGFMA 640
                                                         .|||...||.....|:   :
 Worm   209 ---------------------------------------------SLVSRLTRGHRVKADS---S 225

  Fly   641 AGVCGMGAAAAPLPVTSMGAATTTASSAASTLSALLSANSTGNVDIMEDEDEQERERLSNCPHGT 705
            ....|:||.|                                  |:   ||
 Worm   226 VDSFGLGAGA----------------------------------DV---ED-------------- 239

  Fly   706 PSRVPLIASPLSVPQDSGENTTRNTAFNRHTLQPLSRKTLLLTRRCHRHASGTLYDSTANNTETS 770
                                                    |||.|.
 Worm   240 ----------------------------------------LLTARV------------------- 245

  Fly   771 DDEEYMQHGSEQFVLKKLRYHCDGKDCREAEDSEEEDEKADGRQVPISLVLLILASYICVGTVIF 835
                                     :..:.|..|....:.:...||||||:..:..|:.|||.||
 Worm   246 -------------------------EMEQLEVRETAAAQLESMTVPISLVVFTMLGYLGVGTTIF 285

  Fly   836 ALWENWSLVDGAYFCFVTLSTIGYGDFVPARSF-NGPELQ--LYACCAYLLLGLVLVAMSFSILE 897
            .:||.|:.::..||||::|:|||:||..|:.|. |..|.|  |.....|||.|:.|:||.|::.:
 Worm   286 KVWEGWTFLESFYFCFISLTTIGFGDKFPSTSVSNTDEAQEKLVITSIYLLFGMALLAMCFNLAQ 350

  Fly   898 TQLMWKCKRIAVRLKLARAD 917
            .::..|.:.||.:.:....|
 Worm   351 EEVQNKTRWIADKFRSKEDD 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168	27/55 (49%)
		Ion_trans_2	822..896	CDD:285168	33/76 (43%)
twk-48	NP_001022681.1	Ion_trans_2	<117..176	CDD:285168	28/149 (19%)
		Ion_trans_2	272..355	CDD:285168	33/82 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	57	1.000	Domainoid score	I7277
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920