DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1688 and twk-43

DIOPT Version :9

Sequence 1:	NP_610516.1	Gene:	CG1688 / 36005	FlyBaseID:	FBgn0027589	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_872137.2	Gene:	twk-43 / 3565024	WormBaseID:	WBGene00006693	Length:	597	Species:	Caenorhabditis elegans

Alignment Length:	324	Identity:	69/324 - (21%)
Similarity:	132/324 - (40%)	Gaps:	80/324 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 GLVLLVIGYSVLGGLLFPLLE-APQDISKSAAIAKSRED------------CLRELWIITEKLNV 129
            |:||.|..|...|.||...:| .|..:.:|..:.::.:|            |:.:   ...|::.
Worm    43 GIVLFVGIYVYAGALLIQYIERIPVKVEESFRLRRNSQDDMPIIPLDRSKECVLQ---ALRKMSQ 104

  Fly   130 LYERNWTMLVHEQLRRFEGSIVAATRQGSAGSSGGGGAGLFHEGSASALGHFGYDAGDSQSWSFS 194
            :.:.|.:.| |..:...|....:..::.........|:....:.||.||..|....|..| |:.:
Worm   105 ISKGNCSQL-HNNVNLLENCYASDLQKLKTIYDSSEGSKAPEQQSAVALKKFVIVDGFEQ-WTTT 167

  Fly   195 EALLYSVTVITTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLGALLADGLQC---TYVRL 256
            :|:|:..|||||||:|::.|::..|::..|.|..:|:|..:|.::::|..||..|:.   .::.|
Worm   168 DAILFCFTVITTIGYGNVAPQSFWGRVFVIIYGTIGIPTAMMAIANVGKFLATLLKSWTRPFLLL 232

  Fly   257 CCQLQRHQEHRRKSTPGTSTPSASSAANSREKDTDKRSKRRMANCKGCQYDAANSETSLNDCLEY 321
            |.::::..:  :|...|...               |.::|.|.:.|
Worm   233 CRKMKKRMQ--KKDQNGNEI---------------KETQRLMESSK------------------- 261

  Fly   322 GQKGKLPPDKKEGDACQLLRNLNPQQHFYQQQQQQPQQPDV---------MLMTTTSGSALLKY 376
             :|.|    |.|.|.         ..|..::.:::.::.||         .|:...:||.|:.|
Worm   262 -KKAK----KIEDDI---------SSHEDEEAEEEVEESDVTETIVLFVAFLVYIIAGSLLMSY 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168	20/55 (36%)
CG1688	NP_610516.1	Ion_trans_2	822..896	CDD:285168
twk-43	NP_872137.2	Ion_trans_2	<162..218	CDD:285168	20/56 (36%)
twk-43	NP_872137.2	Ion_trans_2	298..372	CDD:285168	5/14 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010