DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1688 and CG43155

DIOPT Version :9

Sequence 1:	NP_610516.1	Gene:	CG1688 / 36005	FlyBaseID:	FBgn0027589	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_572720.2	Gene:	CG43155 / 32092	FlyBaseID:	FBgn0262685	Length:	411	Species:	Drosophila melanogaster

Alignment Length:	237	Identity:	67/237 - (28%)
Similarity:	106/237 - (44%)	Gaps:	61/237 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 IDDETDATEFGGLGGVGGAGCGSEMGAKTTAS-LTAKPRSSLRRCCGHLLKLLFSTPGLVLLVIG 85
            :|...||.|.||| ..|.||     |.::||. .:.|.:|:|    .|:        ||::.:..
  Fly    28 LDRRVDAAEGGGL-AKGTAG-----GRRSTACWQSMKWKSAL----NHI--------GLLVSLSI 74

  Fly    86 YSVLGGLLFPLLEAPQDISKSA----AIAKSREDCLRELWIITEKLNVLYERNWTMLVHEQLRRF 146
            |..:|||:|..||.|.::.:.:    .:...||..|..:      ||.....|...|:..:|.::
  Fly    75 YCGVGGLIFRHLERPAEVERLSHLKDIVKTHRERFLHTI------LNNTEVHNLDELLSFELAKY 133

  Fly   147 EGSIVAATRQGSAGSSGGGGAGL-------FHEGSASALGHFGYDAGDSQSWSFSEALLYSVTVI 204
            |    ||.:|.:.|       ||       |.|              ..:.||..:|:.:|.||:
  Fly   134 E----AAVQQAAEG-------GLLIVADKDFPE--------------PYERWSILQAVFFSSTVL 173

  Fly   205 TTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLGALLA 246
            ||||:|::.|.|..|::..|.:||:|:|..|..::..|.|.|
  Fly   174 TTIGYGNIVPVTTGGRVFCICFALIGIPFTLTVIADWGRLFA 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168	23/56 (41%)
CG1688	NP_610516.1	Ion_trans_2	822..896	CDD:285168
CG43155	NP_572720.2	Ion_trans_2	<157..214	CDD:285168	21/56 (38%)
		Ion_trans	<240..314	CDD:278921
		Ion_trans_2	<266..319	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461291
Domainoid	1	1.000	51	1.000	Domainoid score	I4317
eggNOG	1	0.900	-	-		E1_KOG1418
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
	8	7.850