Protein Alignment CG1688 and Kcna5

DIOPT Version :10

• Sequence 1: NP_610516.1
• Gene: CG1688 / 36005
• FlyBaseID: FBgn0027589
• Length: 918
• Species: Drosophila melanogaster
• Sequence 2: NP_037104.1
• Gene: Kcna5 / 25470
• RGDID: 2953
• Length: 602
• Species: Rattus norvegicus
• Alignment Length: 185
• Identity: 38/185 - (20%)
• Similarity: 65/185 - (35%)
• Gaps: 41/185 - (22%)

  Fly   166 GAGLFHEGSASALGHFGYDAGDSQSWSFSEALLYSVTVITTIGHGSLTPRTAAGKLATIFYALVG 230
            |..||    :||:.....|...|...|..:|..::|..:||:|:|.:.|.|..||:.....|:.|
  Rat   433 GVILF----SSAVYFAEADNHGSHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAG 493

  Fly   231 VPLMLMCLSSLGALLADGLQCTYVRLCCQLQRHQEHRRKSTPGTSTPSASSAANSREKDTDKRSK 295
            |    :.::....::.......|         |:|          |.....||...|:...:|..
  Rat   494 V----LTIALPVPVIVSNFNYFY---------HRE----------TDHEEQAALKEEQGNQRRES 535

  Fly   296 ------RRMANCKGCQYDAANSETSLNDCLEYGQKGKLPPDKKEGDACQLLRNLN 344
                  :|..:|....:.........:|.:   ::|..|.:|     |.|....|
  Rat   536 GLDTGGQRKVSCSKASFCKTGGSLESSDSI---RRGSCPLEK-----CHLKAKSN 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	177..247	CDD:462301	17/69 (25%)
		Ion_trans_2	822..896	CDD:462301
Kcna5	NP_037104.1	Tetramerization domain. /evidence=ECO:0000250|UniProtKB:P22460	1..202
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	58..107
		BTB_POZ	111..237	CDD:453885
		Ion_trans	240..515	CDD:459842	23/98 (23%)
		S4-S5 linker. /evidence=ECO:0000250|UniProtKB:P63142	407..420
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	469..474		2/4 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	523..543		3/19 (16%)
		PDZ-binding	600..602