Protein Alignment CG1688 and Kcna2

DIOPT Version :10

• Sequence 1: NP_610516.1
• Gene: CG1688 / 36005
• FlyBaseID: FBgn0027589
• Length: 918
• Species: Drosophila melanogaster
• Sequence 2: NP_037102.1
• Gene: Kcna2 / 25468
• RGDID: 2950
• Length: 499
• Species: Rattus norvegicus
• Alignment Length: 169
• Identity: 40/169 - (23%)
• Similarity: 68/169 - (40%)
• Gaps: 25/169 - (14%)

  Fly   166 GAGLFHEGSASALGHFGYDAGDSQSWSFSEALLYSVTVITTIGHGSLTPRTAAGKLATIFYALVG 230
            |..||    :||:.....|..|||..|..:|..::|..:||:|:|.:.|.|..||:.....|:.|
  Rat   338 GVILF----SSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAG 398

  Fly   231 -------VPLMLMCLS------SLGALLADGLQCTYVRLCCQLQRHQEHRRKSTPGTSTPS---- 278
                   ||:::...:      :.|...|..||.|   .|.::....:.::..:..|.:.|
  Rat   399 VLTIALPVPVIVSNFNYFYHRETEGEEQAQYLQVT---SCPKIPSSPDLKKSRSASTISKSDYME 460

  Fly   279 ASSAANSREKDTDKRSKRRMANCKGCQYDAANSETSLND 317
            .....|:..:|. :....:.|||.....:..|....|.|
  Rat   461 IQEGVNNSNEDF-REENLKTANCTLANTNYVNITKMLTD 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	177..247	CDD:462301	21/82 (26%)
		Ion_trans_2	822..896	CDD:462301
Kcna2	NP_037102.1	Tetramerization domain. /evidence=ECO:0000305|PubMed:11007484	1..125
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26
		BTB_POZ	33..159	CDD:453885
		Ion_trans	162..420	CDD:459842	24/85 (28%)
		S4-S5 linker. /evidence=ECO:0000305|PubMed:16002579	312..325
		Selectivity filter. /evidence=ECO:0000305	374..379		2/4 (50%)
		PDZ-binding. /evidence=ECO:0000269|PubMed:7477295	497..499		1/2 (50%)