Protein Alignment CG1688 and Kcnk13

DIOPT Version :10

• Sequence 1: NP_610516.1
• Gene: CG1688 / 36005
• FlyBaseID: FBgn0027589
• Length: 918
• Species: Drosophila melanogaster
• Sequence 2: NP_666149.1
• Gene: Kcnk13 / 217826
• MGIID: 2384976
• Length: 405
• Species: Mus musculus
• Alignment Length: 260
• Identity: 69/260 - (26%)
• Similarity: 93/260 - (35%)
• Gaps: 80/260 - (30%)

  Fly    37 VGGAGCGSEMGAKTTASLTAKPRSSLRRCCGHLLK-----LLFSTPGLVLLVIGYSVLGGLLFPL 96
            :.|.|||            ..|        |||.:     ||.:  ||:||   |.:.|..:|..
Mouse     1 MAGRGCG------------CSP--------GHLNEDNARFLLLA--GLILL---YLLGGAAVFSA 40

  Fly    97 LEAPQDISKSAAIAKSREDCLRELWIITEKL-NVLYERNWTMLVHEQLRRFEGSIVAATRQGSAG 160
            ||..|::.     ||.|       |  .|:| |.....|   |..|:||.|......|||.|...
Mouse    41 LELAQELQ-----AKQR-------W--EERLANFSRGHN---LSREELRGFLRHYEEATRAGIRM 88

  Fly   161 SSGGGGAGLFHEGSASALGHFGYDAGDSQSWSFSEALLYSVTVITTIGHGSLTPRTAAGKLATIF 225
            .|                        ....|.|:.|..:..||::|||.|..||.|..||:..||
Mouse    89 DS------------------------VRPRWDFTGAFYFVGTVVSTIGFGMTTPATTGGKIFLIF 129

  Fly   226 YALVGVPLMLMCLSSLGALLADGLQCTYVRLCCQLQRHQEHRRKSTPGTSTPSASSAANSREKDT 290
            |.|:|....::..:.....|...:.|. :|.|     ||:..|:.  |..|.....|....|.|:
Mouse   130 YGLIGCASTILFFNLFLERLITVIACV-MRSC-----HQQQLRRR--GAVTQDNMKAPEKGEADS 186

  Fly   291  290
            Mouse   187  186

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	177..247	CDD:462301	20/69 (29%)
		Ion_trans_2	822..896	CDD:462301
Kcnk13	NP_666149.1	Ion_trans_2	84..150	CDD:462301	21/89 (24%)
		Selectivity filter 1. /evidence=ECO:0000250|UniProtKB:P57789	110..115		3/4 (75%)
		Ion_trans_2	203..285	CDD:462301
		Selectivity filter 2. /evidence=ECO:0000250|UniProtKB:P57789	237..242