DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1688 and twk-13

DIOPT Version :9

Sequence 1:	NP_610516.1	Gene:	CG1688 / 36005	FlyBaseID:	FBgn0027589	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_001122984.1	Gene:	twk-13 / 192077	WormBaseID:	WBGene00006668	Length:	625	Species:	Caenorhabditis elegans

Alignment Length:	320	Identity:	81/320 - (25%)
Similarity:	135/320 - (42%)	Gaps:	94/320 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 GLVLLVIGYSVLGGLLFPLLEAPQDISKSAAIAKSREDCLRELWIITEKLNVLYERNWTMLVHEQ 142
            |||||.|||:::|.|.|...|.|.:       .:.|.:..|.   |.|..|.:.::.|.|
Worm   118 GLVLLSIGYTLIGALCFHHYEKPYE-------QQLRNETSRR---IGELKNRVMDQLWRM----- 167

  Fly   143 LRRFEGSIVAATRQGSAGSSGGGGAGLFHEGSASALGHFGYD------------AGDSQ-SWSFS 194
                       :..|:|.|:....|   ::|....:....:|            .||.. .|||.
Worm   168 -----------SNNGTAYSTWRQTA---NDGMDELIRDVFWDYTRNYMTPDDVIYGDGPIKWSFM 218

  Fly   195 EALLYSVTVITTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLGALLADGLQCTY-VRL-- 256
            .::.:|.|.|||||:|.:.|||..|::|.|||||:|:||:|:.::.:|..||     || ::|
Worm   219 SSIFFSWTAITTIGYGHIVPRTDEGRVAIIFYALLGIPLILVTIADIGRFLA-----TYIIKLHH 278

  Fly   257 --------------------CCQLQRHQEH-----------RRKSTPGTSTPSASSAANSREKDT 290
                                ||.::..:.|           .:|..|..:.|:.::.|.|....|
Worm   279 GYMAVMSFVTNSCLKCIKWACCWIRLPRRHIPMPTLELLQRTQKLYPNNNNPTVAATAASAGGGT 343

  Fly   291 DKRSKRRMANCKGCQYDAANSE--TSLNDCLEYGQKGKLPPDKKEGDACQLLRNLNPQQH 348
            .:|.|::..|..    ||...:  :.:||..|.|:      ::.||:..:.:: .:|..|
Worm   344 GRRKKQQRDNVS----DAGTFDNISEINDGSEGGE------NENEGEEEEQIQ-FDPSNH 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168	27/55 (49%)
CG1688	NP_610516.1	Ion_trans_2	822..896	CDD:285168
twk-13	NP_001122984.1	Ion_trans_2	<214..269	CDD:285168	26/54 (48%)
		Ion_trans	<398..464	CDD:278921
		Ion_trans_2	403..478	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.020