DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1688 and twk-32

DIOPT Version :9

Sequence 1:	NP_610516.1	Gene:	CG1688 / 36005	FlyBaseID:	FBgn0027589	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_506416.2	Gene:	twk-32 / 192075	WormBaseID:	WBGene00006684	Length:	614	Species:	Caenorhabditis elegans

Alignment Length:	149	Identity:	44/149 - (29%)
Similarity:	65/149 - (43%)	Gaps:	28/149 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   749 RRCHRHASGTLYDSTANNTETSDDEEYMQHGSEQFVLKKLRYHCDGKDCREAEDSEEEDEKADGR 813
            ||..|..||.:      ..|:....:.:..|.|..|.:.|..|.               |.|...
Worm   198 RRYKRWKSGRI------RRESMKVGQVIIAGGEDEVAEFLWTHL---------------EHAQFV 241

  Fly   814 QVPISLVLLILASYICVGTVIFALWENWSLVDGAYFCFVTLSTIGYGDFVPARS-FNGPELQLYA 877
            :||..||:.||..||.:.:.|.:..|||:::||.||..:::.|||:||.||... |..|.|.:
Worm   242 EVPFLLVIGILLLYIGLSSWIISWVENWNMMDGFYFVMMSVLTIGFGDLVPRNEIFAVPILFI-- 304

  Fly   878 CCAYLLLGLVLVAMSFSIL 896
                :|.||||......::
Worm   305 ----ILAGLVLTTTCIDVV 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168
CG1688	NP_610516.1	Ion_trans_2	822..896	CDD:285168	27/74 (36%)
twk-32	NP_506416.2	Ion_trans_2	<125..180	CDD:285168
		Ion_trans_2	251..325	CDD:285168	27/75 (36%)
		FN3	392..485	CDD:238020
		FN3	491..580	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810