DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1688 and twk-45

DIOPT Version :9

Sequence 1:	NP_610516.1	Gene:	CG1688 / 36005	FlyBaseID:	FBgn0027589	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_001122742.2	Gene:	twk-45 / 190614	WormBaseID:	WBGene00006695	Length:	508	Species:	Caenorhabditis elegans

Alignment Length:	205	Identity:	57/205 - (27%)
Similarity:	98/205 - (47%)	Gaps:	36/205 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 LVLLVIGYSVLGGLLFPLLEAPQDISKSAAIAKSREDCLRELWIITEKLNVL--------YERNW 135
            |:.::..|..|||.||..||:|::|.:.....||..:.::     .|.::::        .:||
Worm    89 LISILAAYICLGGFLFQKLESPREIEELQETLKSMNEIIK-----NETMDIIKITLTTNGEDRN- 147

  Fly   136 TMLVHEQLRRFEGSIVAATRQGSAGSSGGGGAGLFHEGSASALGHFGYDAGDSQSWSFSEALLYS 200
             ..:.:.||.:. .|:..|.            |.|| |||   .|...:...:..|.||.|..||
Worm   148 -QKLGDLLRAYH-RILLETE------------GKFH-GSA---WHKSENLDMNLMWYFSSATFYS 194

  Fly   201 VTVITTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLGALLADGLQCTYVRLCCQLQ--RH 263
            :|:.:|||:|::|.:|..||..::.||.:|:|:||:.|..:|......:...|:.:..:.:  |.
Worm   195 MTLFSTIGYGTITCQTFWGKTVSMVYASIGLPIMLLVLGDIGVWFQKVMTNAYIFVMLKYKSLRK 259

  Fly   264 Q--EHRRKST 271
            |  |.:||.|
Worm   260 QSIEIKRKET 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168	23/55 (42%)
CG1688	NP_610516.1	Ion_trans_2	822..896	CDD:285168
twk-45	NP_001122742.2	Ion_trans_2	<185..241	CDD:285168	23/55 (42%)
twk-45	NP_001122742.2	Ion_trans_2	278..354	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020