DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1688 and twk-40

DIOPT Version :9

Sequence 1:	NP_610516.1	Gene:	CG1688 / 36005	FlyBaseID:	FBgn0027589	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_001255206.1	Gene:	twk-40 / 189006	WormBaseID:	WBGene00006691	Length:	436	Species:	Caenorhabditis elegans

Alignment Length:	256	Identity:	59/256 - (23%)
Similarity:	107/256 - (41%)	Gaps:	63/256 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 LTAKPRSSLRRCCGHLLKLLFSTPGLVLLVIGYSVLGGLLFPLLEAPQDISKSAAIAK----SRE 114
            :|::|.::.:.    ..:::.:...|::|.:.|...|..||..||.|.::...|...:    .:.
Worm    39 ITSRPMATWKT----YARIILAHVSLIVLSVVYVGFGAFLFYQLEQPNEVEVRARNIERFNIHKR 99

  Fly   115 DCLRELW---------IITEKLNVLYERNWTMLVHEQLRRFEGSIVAATRQGSAGSSGGGGAGLF 170
            ..:..||         .:.|.|.|.|..|.|.::.|   .|:...:.|......|..
Worm   100 QMIEHLWEMRESGIGQHVVEDLAVKYVDNVTRILFE---AFDTHCIGAKHLRPGGED-------- 153

  Fly   171 HEGSASALGHFGYDAGDSQSWSFSEALLYSVTVITTIGHGSLTPRTAAGKLATIFYALVGVPLML 235
                            :..:|::..||.::.|::||||:|:|||.|..|||..|.|||.||||:|
Worm   154 ----------------EDYNWTYMTALFFTTTLLTTIGYGNLTPVTGRGKLLCILYALFGVPLIL 202

  Fly   236 MCLSSLGALLADGLQCTY-----VRLCCQLQRHQEHRRKSTPGTSTPSASSAANSREKDTD 291
            :.::.:|..|::.:...|     :|..|..|::              |..|:.:.:.|:.|
Worm   203 ITVADIGKFLSENIVQLYTWYRKLREKCSKQKY--------------SVISSKDDKNKEGD 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168	27/55 (49%)
CG1688	NP_610516.1	Ion_trans_2	822..896	CDD:285168
twk-40	NP_001255206.1	Ion_trans_2	<174..214	CDD:285168	21/39 (54%)
twk-40	NP_001255206.1	Ion_trans_2	269..343	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020