DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1688 and twk-44

DIOPT Version :9

Sequence 1:	NP_610516.1	Gene:	CG1688 / 36005	FlyBaseID:	FBgn0027589	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_509942.4	Gene:	twk-44 / 181349	WormBaseID:	WBGene00006694	Length:	733	Species:	Caenorhabditis elegans

Alignment Length:	278	Identity:	76/278 - (27%)
Similarity:	116/278 - (41%)	Gaps:	87/278 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 SLTAKPRSSLRRCCGHLLKLLFSTPGL-----VLLVIGYSVLGGLLFPLLEAPQD----ISKSAA 108
            |:..:| |.|:|... ||::::....:     ::|:|.|||||||:|..:|.|.:    ..|...
Worm    43 SIVNRP-SKLKRFVS-LLQIIYDKSRVHYLVPIILLIAYSVLGGLIFWSIERPNEEIMLADKRNY 105

  Fly   109 IAKSREDCLRELWIITEKL---NVLYERN-WTMLVH----------------------------- 140
            ||...:|.:..|..|..:|   |.:|..| :.:::|
Worm   106 IAALTDDLVEVLMQIHNRLIDFNRVYSNNTYLLMIHYRGYRKFALNQIHKSVYWYTLSTFYLTEH 170

  Fly   141 -------------EQL--RRFE---GSIVAA---TRQ--------GSAGSSGGG---------GA 167
                         |||  |.||   |.|.|.   |.|        |..|::.|.         ..
Worm   171 EMHKVVALRPKNPEQLWKRHFESNFGRIRALKNYTEQLCLRCWELGVEGANQGWTRYNYSLMVNQ 235

  Fly   168 GLFHEGSASALGHFGYDAGDSQSWSFSEALLYSVTVITTIGHGSLTPRTAAGKLATIFYALVGVP 232
            .:....::..|||.     .:..|:|..|:..:||..||||:|::|.:|..||||.:.||:||:|
Worm   236 SVEEYNNSVGLGHV-----LTPVWTFWNAMFLAVTTYTTIGYGNITAKTKLGKLAAMVYAVVGIP 295

  Fly   233 LMLMCLSSLGALLADGLQ 250
            |:||.|...|.|...||:
Worm   296 LVLMILHKSGRLFLMGLE 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168	27/55 (49%)
CG1688	NP_610516.1	Ion_trans_2	822..896	CDD:285168
twk-44	NP_509942.4	Ion_trans_2	237..308	CDD:285168	29/75 (39%)
twk-44	NP_509942.4	Ion_trans_2	354..>397	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810