DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1688 and unc-58

DIOPT Version :9

Sequence 1:	NP_610516.1	Gene:	CG1688 / 36005	FlyBaseID:	FBgn0027589	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_001360793.1	Gene:	unc-58 / 181224	WormBaseID:	WBGene00006792	Length:	616	Species:	Caenorhabditis elegans

Alignment Length:	236	Identity:	61/236 - (25%)
Similarity:	103/236 - (43%)	Gaps:	57/236 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 LKLLFSTPGLVL--LVIGYSVLGGLLFPLLEAPQDISKSAAIAKSREDCLRELWIITEKLNVLYE 132
            :|:|  ||.::|  ::|||..||..:..|||     :::..:|:|     ::|..:|..::....
Worm   189 IKIL--TPHVILVSVLIGYLCLGAWILMLLE-----TRTELLARS-----KKLVRLTNLMSNFTA 241

  Fly   133 RNWTMLVHEQLRRFEGSIVAATRQGSAGSSGGGGAGLFHEGSASALGHFGYDAGDSQ-------- 189
            .:|.||.:.|             .|.:....|..|..|.|.....     .:..|.:
Worm   242 ESWKMLNNAQ-------------HGVSNMDEGEWAATFREWMVRV-----SETVDDRRPIRRELN 288

  Fly   190 ----------SWSFSEALLYSVTVITTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLGAL 244
                      .|:|..|:||.:||:||.|:|.::..|..||:.::.:||||:|||.:..:.:|..
Worm   289 RPDDLSNMHNKWTFPTAILYVLTVLTTCGYGEVSVDTDVGKVFSVAFALVGIPLMFITAADIGKF 353

  Fly   245 LADGL------QCTYVRLCCQ-LQRHQEHRRKSTPGTSTPS 278
            |::.|      ....||...| :.|.:..||||...|..|:
Worm   354 LSETLLQFVSFWNRSVRKVKQWMSRIRHGRRKSLQSTGGPN 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168	23/55 (42%)
CG1688	NP_610516.1	Ion_trans_2	822..896	CDD:285168
unc-58	NP_001360793.1	Ion_trans_2	<299..355	CDD:369572	22/55 (40%)
unc-58	NP_001360793.1	Ion_trans_2	435..498	CDD:369572
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010