DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1688 and twk-26

DIOPT Version :9

Sequence 1:	NP_610516.1	Gene:	CG1688 / 36005	FlyBaseID:	FBgn0027589	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_508522.2	Gene:	twk-26 / 180592	WormBaseID:	WBGene00006679	Length:	519	Species:	Caenorhabditis elegans

Alignment Length:	207	Identity:	54/207 - (26%)
Similarity:	101/207 - (48%)	Gaps:	43/207 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 LVLLVIGYSVLGGLLFPLLEAPQDISKSAAIAKSREDCLRELWII---------TEKLNVLYERN 134
            |:.|::||..|||.:|..||:|:::          || |:|..::         |:.:||....|
Worm    89 LIALLVGYVFLGGFMFEKLESPREL----------ED-LKETIVLMQGIIDEETTDIINVTLSTN 142

  Fly   135 WTMLVH---EQLRRFEGSIVAATRQGSAGSSGGGGAGLFHEGSASALGHFGYDAGDSQSWSFSEA 196
            .|..|:   :.::|:..:::.|             .|.||    .::.|...:......|.||.|
Worm   143 GTDRVNKLAKLIKRYYKTMLEA-------------EGRFH----GSVWHKAENLDMHLMWYFSSA 190

  Fly   197 LLYSVTVITTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLGALLADGLQCTYVRLCC--- 258
            ..||:|:.:|||:|:::.:|..|:..::.||.:|:|:||:.|..:|......|...|:.|..
Worm   191 TFYSMTLFSTIGYGTISCQTVWGRTLSMIYASIGLPIMLVVLGDIGEWFQKILTNGYIFLLLKYK 255

  Fly   259 QLQRHQEHRRKS 270
            :|::...:|:|:
Worm   256 KLRKQPVNRKKN 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168	21/55 (38%)
CG1688	NP_610516.1	Ion_trans_2	822..896	CDD:285168
twk-26	NP_508522.2	Ion_trans_2	<185..241	CDD:285168	21/55 (38%)
twk-26	NP_508522.2	Ion_trans_2	278..>327	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920