DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1688 and twk-46

DIOPT Version :9

Sequence 1:	NP_610516.1	Gene:	CG1688 / 36005	FlyBaseID:	FBgn0027589	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_741678.1	Gene:	twk-46 / 180252	WormBaseID:	WBGene00006696	Length:	319	Species:	Caenorhabditis elegans

Alignment Length:	173	Identity:	47/173 - (27%)
Similarity:	76/173 - (43%)	Gaps:	41/173 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 GLVLLVIGYSVLGGLLFPLLEAPQDISKSAAIAKSREDCLRELWIITEKLNVLYERNW-TMLVHE 141
            ||.:.|: |..:|.::|..:|.|            .|...||.::.       |:..| ..|:
Worm    30 GLGVAVV-YLFVGAIVFVRIEYP------------LEKIEREAYLD-------YQNQWRDRLI-- 72

  Fly   142 QLRRFEGSIVAATRQGSAGSSGGGGAGLFHEGSASALGHFGYDAG--DSQSWSFSEALLYSVTVI 204
            ||...|..|                ..||.....:||.....|..  ...:|:|.:|..::.|:|
Worm    73 QLDIDESEI----------------DKLFLNIREAALNGIWMDRNLTSDPNWTFGQAFFFAGTLI 121

  Fly   205 TTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLGALLAD 247
            :|:|:|.::|||..|||.||.|.::|:||.|..||::.|.:.:
Worm   122 STVGYGRVSPRTEYGKLFTILYCVIGIPLTLALLSAIVARMRE 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168	24/55 (44%)
CG1688	NP_610516.1	Ion_trans_2	822..896	CDD:285168
twk-46	NP_741678.1	Ion_trans_2	<107..164	CDD:285168	24/56 (43%)
twk-46	NP_741678.1	Ion_trans_2	198..274	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910