DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1688 and twk-36

DIOPT Version :9

Sequence 1:	NP_610516.1	Gene:	CG1688 / 36005	FlyBaseID:	FBgn0027589	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_507485.2	Gene:	twk-36 / 180164	WormBaseID:	WBGene00006688	Length:	562	Species:	Caenorhabditis elegans

Alignment Length:	187	Identity:	50/187 - (26%)
Similarity:	92/187 - (49%)	Gaps:	31/187 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 LVLLVIGYSVLGGLLFPLLEAPQDISKSAAIAKSREDCLREL-WIITEKLNVLYERNWTMLVHEQ 142
            |::|.:.|::||..:|.|:|...:.|:.....::.:..|.|| .:::|.:|...:.:    .|::
Worm   173 LLVLALIYTLLGATVFYLIEGSNEKSRLHVREQNLDKLLDELATVLSEAVNDPEQSS----EHQR 233

  Fly   143 LRRF-EGSIVAATRQGSAGSSGGGGAGLFHEGSASALGHFGYDAGDSQSWSFSEALLYSVTVITT 206
            ::.| :.|.::..:               ||.......::..:..|:..|:||.|..:|:.|.||
Worm   234 MKEFIKESYISLQK---------------HEEQYKWSTYYRLEHPDNLKWTFSSAFFFSMNVYTT 283

  Fly   207 IGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLG--------ALLADGLQCTYVR 255
            .|:||::.:|.:|:|.|:.||...||:.|:.|..||        .|.|.||  |.||
Worm   284 TGYGSISAQTFSGQLFTMIYAFCFVPVTLVILRDLGQMFLVNFTKLYAHGL--TAVR 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168	24/63 (38%)
CG1688	NP_610516.1	Ion_trans_2	822..896	CDD:285168
twk-36	NP_507485.2	Ion_trans_2	255..322	CDD:285168	24/66 (36%)
		Ion_trans_2	361..432	CDD:285168
		Ion_trans	<363..452	CDD:278921
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910