DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1688 and twk-33

DIOPT Version :9

Sequence 1:	NP_610516.1	Gene:	CG1688 / 36005	FlyBaseID:	FBgn0027589	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_001309463.1	Gene:	twk-33 / 180161	WormBaseID:	WBGene00006685	Length:	617	Species:	Caenorhabditis elegans

Alignment Length:	253	Identity:	61/253 - (24%)
Similarity:	105/253 - (41%)	Gaps:	52/253 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 PSQLDCSIDDETD-ATEFGGLGGVGGAGCGSEMGAKTTASLTAKPRSSLRRCCGHLLKLLFSTPG 78
            |.:|...:...|| |:.|...|.         ||.....:|....: |:.....|..::.|....
Worm   164 PGRLQHRLSVHTDAASRFSSPGA---------MGEPVVPTLRRFDK-SMYWFAFHRKQIGFRHFS 218

  Fly    79 LVLLVIGYSVLGGLLFPLLEAPQDISKSAAIAKSREDCLREL-WIITEKLN----VLYERNWTML 138
            :|:||:.|::||.::|..:|:..:.:|:.....:.|..|..| ..|||.:|    ...|....:.
Worm   219 VVILVLLYTLLGAVMFWTVESRHEKAKTLDHVNNLEHLLDRLAENITESVNNINTTTTEEEMKVY 283

  Fly   139 VHE---QLRRFEGSIVAATRQGSAGSSGGGGAGLFHEGSASALGHFGYDAGDSQSWSFSEALLYS 200
            :.|   :|.:.||.                     ::||.    ::..:|.|:..|:|..|..:|
Worm   284 IREAYIELMKLEGQ---------------------YKGST----YYKLEADDNWKWTFESAFFFS 323

  Fly   201 VTVITTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLG--------ALLADGLQ 250
            :.|.||.|:||:.|.:..|::....|..:.||:.|:.|..||        .|.|.|:|
Worm   324 MNVYTTTGYGSIAPESTLGQVLVCVYGFIFVPVTLVVLRDLGQFFLVHLTKLYAHGIQ 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168	20/63 (32%)
CG1688	NP_610516.1	Ion_trans_2	822..896	CDD:285168
twk-33	NP_001309463.1	Hid1	<9..141	CDD:301632
		Ion_trans_2	300..368	CDD:285168	23/71 (32%)
		Ion_trans	<404..498	CDD:278921
		Ion_trans_2	407..491	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910