Protein Alignment CG1688 and egl-23

DIOPT Version :9

• Sequence 1: NP_610516.1
• Gene: CG1688 / 36005
• FlyBaseID: FBgn0027589
• Length: 918
• Species: Drosophila melanogaster
• Sequence 2: NP_001255775.1
• Gene: egl-23 / 178358
• WormBaseID: WBGene00001190
• Length: 726
• Species: Caenorhabditis elegans
• Alignment Length: 611
• Identity: 122/611 - (19%)
• Similarity: 192/611 - (31%)
• Gaps: 224/611 - (36%)

  Fly   187 DSQSWSFSEALLYSVTVITTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLGALLADGLQC 251
            |...|||.::||::.|||||||:|::.|||..|:|..|.|.|:|:|..|:.::.||..:::  ..
 Worm   216 DVSEWSFMDSLLFAFTVITTIGYGNVAPRTFGGRLFVIGYGLIGIPFTLLAIADLGKFISE--MM 278

  Fly   252 TYVRLCCQLQRHQEHRRKSTPGTSTPSASSAANSREKDTDKRSKRRMANCKGCQYDAANSETSLN 316
            ...:..|: :..::.::...|........|..:..||..|...         .:.:...||.|..
 Worm   279 VEAKSFCR-KTWKKLKKAWNPNFIRAKDLSNTDIEEKILDNEK---------IENEPETSEVSEE 333

  Fly   317 DCLEYGQKGKLPPDKKEGDACQL--------------LRNLNPQQHFYQQQQQQ----------- 356
            :           .|..|.:|..|              |....|...|::.....
 Worm   334 E-----------DDLTETEATSLFILFLVYIAFGGFMLAAYEPDMDFFKAVYFNFVTLTSIGLGD 387

  Fly   357 --PQQPDVMLMT---TTSGSALLKYAPQQQQLQQQQQLSTATLPRQHH----------------- 399
              |:....||:|   ...|.||...|         .:::...|.:.|:
 Worm   388 IVPRSETYMLITIVYIAIGLALTTIA---------IEIAADALKKLHYFGRKIENVGNVAIWFGG 443

  Fly   400 -QMQLQQQQQQLQQNFVAVPSSM-----------------------LRMPLTVPPN-------CY 433
             ::.::...:.|...| .:|:::                       ||.|...||:       ..
 Worm   444 KKITMKALVKNLGDQF-NLPTTVVKNLNLDHFVDQAIKVEEGEIETLRPPPYEPPSDRFEAEFAD 507

  Fly   434 APATATIYFPFGHAPSAPGSPAHNQAHPTQNPNGNALGNTTLGSQPLVKYHTIHLQPASGKHRVL 498
            .|....|..|   .|:.|.||......|:..|         :..:||         |:
 Worm   508 EPECEWIRDP---TPTPPPSPQPVYRLPSPKP---------VTPEPL---------PS------- 544

  Fly   499 ASGLQDATAVNLVTAS---EASTSTLEAI------------TLPPPPAYQTASVHAVRRAKFVAK 548
                ...|.|:|..|:   |.|....|.|            |.||||                .:
 Worm   545 ----PTITDVSLAIATPSPEESDDDQELILPSPEPSPVREPTPPPPP----------------RE 589

  Fly   549 PLPQEINALMDCGTGSPDLSGRHDLLPPPHSGSP----ATGTAASPLLTYTAAA----------- 598
            |.|:|       .|..|: ..|....|||....|    |...||.....|:..|
 Worm   590 PTPRE-------PTPEPE-PVREPTPPPPPPAKPRPLTAAEIAAQKRKAYSEEAWRRYQEYQKQW 646

  Fly   599 --------TSPQLSAGIKGGSGPAPTAGAPMLVSGAGRGAAALTDNGFMAAGVCGMGAAAAPLPV 655
                    |.....|...|.|...|:..:|              ::|   |||| .|.:.....:
 Worm   647 KKFRQTQKTPAPSGASTSGASTSKPSGTSP--------------ESG---AGVC-TGPSTRSQSI 693

  Fly   656 TSMGAATTTASSA-ASTLSALLSANS 680
            ||:.:..|:.|:. .|..|:.||.:|
 Worm   694 TSVASGKTSRSATPESKKSSHLSGSS 719

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168	26/55 (47%)
		Ion_trans_2	822..896	CDD:285168
egl-23	NP_001255775.1	Ion_trans_2	216..276	CDD:285168	27/59 (46%)
		Ion_trans_2	347..423	CDD:285168	12/84 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010