DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1688 and twk-31

DIOPT Version :9

Sequence 1:	NP_610516.1	Gene:	CG1688 / 36005	FlyBaseID:	FBgn0027589	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_001022884.1	Gene:	twk-31 / 176572	WormBaseID:	WBGene00006683	Length:	1136	Species:	Caenorhabditis elegans

Alignment Length:	271	Identity:	71/271 - (26%)
Similarity:	112/271 - (41%)	Gaps:	54/271 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EQAIKAKQPQPSQLDCSIDDETDATEFGGL---GGVGGAGCGSEMGAKTTASLTAKPRSSLRRCC 66
            |:..|...|:|::. ..:...|.....||.   |.:.|...|..:|...:      |.|.|.:|.
Worm    77 EEYRKPAPPEPTKF-LQVSRTTVRMLAGGFSRAGSLEGVETGGIVGPPMS------PISFLGKCK 134

  Fly    67 GHLLKLLFSTPGLVLLVIGYSVLGGLLFPLLEAPQDISKSAAIAKSREDCLRELWIITEKLNVLY 131
            .:..|.........:|::.||.||..:|.|.|  .|..:...: |.|.| ||.|      .|..:
Worm   135 HYYDKYKLDRISASVLLVLYSFLGAWVFYLFE--HDYEREVKL-KERID-LRML------RNDTF 189

  Fly   132 ERNWTMLVHEQ-LRRFEGSIVAATRQGSAGSSGGGGAGLFHEGSASALGHFGYDAGDSQSWSFSE 195
            :|..:|:..:| |..||...:...::             .|.          ....:...|.:..
Worm   190 QRISSMVFRQQGLANFEEVFIDYEKK-------------LHV----------VRLPECLDWDYWG 231

  Fly   196 ALLYSVTVITTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLGALLADGLQCTYVRLCCQL 260
            ||.|..|:.||||:|::.||||.|:.|::.||:||:||:|..||..|..:.|.|.
Worm   232 ALFYVGTLFTTIGYGNIYPRTALGRAASVVYAIVGIPLVLAILSKCGKWMTDSLS---------- 286

  Fly   261 QRHQEHRRKST 271
            ::.|:||.:.|
Worm   287 EKWQQHRIQIT 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168	26/55 (47%)
CG1688	NP_610516.1	Ion_trans_2	822..896	CDD:285168
twk-31	NP_001022884.1	Ion_trans_2	<226..283	CDD:285168	26/56 (46%)
twk-31	NP_001022884.1	Ion_trans_2	347..423	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920