DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1688 and twk-3

DIOPT Version :9

Sequence 1:	NP_610516.1	Gene:	CG1688 / 36005	FlyBaseID:	FBgn0027589	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_495727.1	Gene:	twk-3 / 174321	WormBaseID:	WBGene00006658	Length:	383	Species:	Caenorhabditis elegans

Alignment Length:	207	Identity:	56/207 - (27%)
Similarity:	88/207 - (42%)	Gaps:	37/207 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 MGAKTTASLTAKPRSSLRRCCGHLLKLLFSTPGLVLLVIGYSVLGGLLFPLLEAPQDISKSAAIA 110
            :.|.:.....|..||.|.:.  ||..|...| ||||..:.|::.|..||..:|.|:::
Worm    14 LSATSKDKKVATDRSLLNKY--HLGPLALHT-GLVLSCVTYALGGAYLFLSIEHPEEL------- 68

  Fly   111 KSREDCLRELWIITEKLNVLYERNWTMLVHEQLRRFEGSIVAATRQGSAGSSGGGGAGLF----- 170
            |.||..:||.    :.|...:..|.|    ..:...|.||...|::..........|..|
Worm    69 KRREKAIREF----QDLKQQFMGNIT----SGIENSEQSIEIYTKKLILMLEDAHNAHAFEYFFL 125

  Fly   171 -HEGSASALGHFGYDAGDSQSWSFSEALLYSVTVITTIGHGSLTPRTAAGKLATIFYALVGVPLM 234
             ||             .....|:||.||:::.|.:..:|:|.:.|.:|.|::..|.|||:|:||.
Worm   126 NHE-------------IPKDMWTFSSALVFTTTTVIPVGYGYIFPVSAYGRMCLIAYALLGIPLT 177

  Fly   235 LMCLSSLGALLA 246
            |:.::..|...|
Worm   178 LVTMADTGKFAA 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168	21/56 (38%)
CG1688	NP_610516.1	Ion_trans_2	822..896	CDD:285168
twk-3	NP_495727.1	Ion_trans_2	<134..190	CDD:285168	21/56 (38%)
twk-3	NP_495727.1	Ion_trans_2	211..283	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7175
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.770