DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1688 and Kcnk7

DIOPT Version :9

Sequence 1:	NP_610516.1	Gene:	CG1688 / 36005	FlyBaseID:	FBgn0027589	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_034739.2	Gene:	Kcnk7 / 16530	MGIID:	1341841	Length:	343	Species:	Mus musculus

Alignment Length:	188	Identity:	42/188 - (22%)
Similarity:	75/188 - (39%)	Gaps:	57/188 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 SLRRCCGHLLKLLFSTPGLVLLVIGYSVLGGLLFPLLEAP-------QDISKSAAIAKSREDCLR 118
            ||:....:||.|:..     ||.:|   ||.::...||.|       |..::.|:.......||.
Mouse     3 SLKPWARYLLLLMAH-----LLAMG---LGAVVLQALEGPPARHLQAQVQAELASFQAEHRACLP 59

  Fly   119 ELWIITEKLNVLYERNWTMLVHEQLRRFEGSIVAATRQGSAGSSGGGGAGLFHEGSASALGHFGY 183
            .                     |.|....|:::.|...|                 .|:||
Mouse    60 P---------------------EALEELLGAVLRAQAHG-----------------VSSLG---- 82

  Fly   184 DAGDSQSWSFSEALLYSVTVITTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSL 241
            ::.::.:|....|||::.:::||.|:|.:.|.::.||...:.||.:|:|..|..:::|
Mouse    83 NSSETSNWDLPSALLFTASILTTTGYGHMAPLSSGGKAFCVVYAALGLPASLALVAAL 140

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168	17/51 (33%)
CG1688	NP_610516.1	Ion_trans_2	822..896	CDD:285168
Kcnk7	NP_034739.2	Ion_trans_2	<89..140	CDD:285168	16/50 (32%)
Kcnk7	NP_034739.2	Ion_trans_2	178..>225	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7175
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850