Protein Alignment CG1688 and Kcna5

DIOPT Version :10

• Sequence 1: NP_610516.1
• Gene: CG1688 / 36005
• FlyBaseID: FBgn0027589
• Length: 918
• Species: Drosophila melanogaster
• Sequence 2: NP_666095.1
• Gene: Kcna5 / 16493
• MGIID: 96662
• Length: 602
• Species: Mus musculus
• Alignment Length: 167
• Identity: 34/167 - (20%)
• Similarity: 59/167 - (35%)
• Gaps: 40/167 - (23%)

  Fly   187 DSQSWSFS---EALLYSVTVITTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLGALLADG 248
            |:|...||   :|..::|..:||:|:|.:.|.|..||:.....|:.||    :.::....::...
Mouse   447 DNQGSHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGV----LTIALPVPVIVSN 507

  Fly   249 LQCTYVRLCCQLQRHQEHRRKSTPGTSTPSASSAANSREKDTDKRSK------RRMANCKGCQYD 307
            ....|         |:|          |.....||...|:...:|..      :|..:|....:.
Mouse   508 FNYFY---------HRE----------TDHEEQAALKEEQGIQRRESGLDTGGQRKVSCSKASFC 553

  Fly   308 AANSETSLNDCLEYGQKGKLPPDKKEGDACQLLRNLN 344
            .........|.:   ::|..|.:|     |.|....|
Mouse   554 KTGGPLESTDSI---RRGSCPLEK-----CHLKAKSN 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	177..247	CDD:462301	17/62 (27%)
		Ion_trans_2	822..896	CDD:462301
Kcna5	NP_666095.1	Tetramerization domain. /evidence=ECO:0000250|UniProtKB:P22460	1..202
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..107
		BTB_POZ	111..237	CDD:453885
		Ion_trans	240..515	CDD:459842	19/80 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	274..297
		S4-S5 linker. /evidence=ECO:0000250|UniProtKB:P63142	407..420
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	469..474		2/4 (50%)
		PDZ-binding	600..602