Protein Alignment CG1688 and Kcnk6

DIOPT Version :10

• Sequence 1: NP_610516.1
• Gene: CG1688 / 36005
• FlyBaseID: FBgn0027589
• Length: 918
• Species: Drosophila melanogaster
• Sequence 2: NP_446258.2
• Gene: Kcnk6 / 116491
• RGDID: 621450
• Length: 313
• Species: Rattus norvegicus
• Alignment Length: 157
• Identity: 47/157 - (29%)
• Similarity: 71/157 - (45%)
• Gaps: 33/157 - (21%)

  Fly    85 GYSVLGGLLFPLLEAPQDISKSAAIAKSREDCLREL-WIITEKLNVLYERNWTMLVHEQLRRFEG 148
            ||..||.||...||.|.:....|.:...||..||.. .:....|:...||
  Rat    16 GYLALGALLVARLERPHEARLRAELGTLREQLLRHSPCVAAHALDAFVER--------------- 65

  Fly   149 SIVAATRQGSAGSSGGGGAGLFHEGSASALGHFGYDAGDSQSWSFSEALLYSVTVITTIGHGSLT 213
             ::||.|.|.|..:...|..               :|.| .:|.|:.||.::.|::||:|:|..|
  Rat    66 -VLAAGRLGRAVLANASGPA---------------NASD-PAWDFASALFFASTLVTTVGYGYTT 113

  Fly   214 PRTAAGKLATIFYALVGVPLMLMCLSS 240
            |.|.|||..:|.:||:|||:.::.|::
  Rat   114 PLTDAGKAFSIVFALLGVPITMLLLTA 140

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	177..247	CDD:462301	24/64 (38%)
		Ion_trans_2	822..896	CDD:462301
Kcnk6	NP_446258.2	Ion_trans_2	<89..146	CDD:462301	22/52 (42%)
		Selectivity filter 1. /evidence=ECO:0000250|UniProtKB:P57789	106..111		2/4 (50%)
		Ion_trans_2	180..259	CDD:462301
		Selectivity filter 2. /evidence=ECO:0000250|UniProtKB:P57789	214..219
		Lysosomal targeting signal. /evidence=ECO:0000269|PubMed:28381826	282..290
		Lysosomal targeting signal. /evidence=ECO:0000269|PubMed:28381826	308..312