DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1688 and KCNK7

DIOPT Version :9

Sequence 1:	NP_610516.1	Gene:	CG1688 / 36005	FlyBaseID:	FBgn0027589	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_203133.1	Gene:	KCNK7 / 10089	HGNCID:	6282	Length:	307	Species:	Homo sapiens

Alignment Length:	172	Identity:	39/172 - (22%)
Similarity:	68/172 - (39%)	Gaps:	42/172 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 FSTPGLV----LLVIGYSVLGGLLFPLLEAPQDISKSAAIAKSREDCLRELWIITEKLNVLYERN 134
            :|..||:    ||.:|   ||.::|..||.|......|.              :..:|......:
Human     7 WSRYGLLVVAHLLALG---LGAVVFQALEGPPACRLQAE--------------LRAELAAFQAEH 54

  Fly   135 WTMLVHEQLRRFEGSIVAATRQGSAGSSGGGGAGLFHEGSASALGHFGYDAGDSQSWSFSEALLY 199
            ...|....|....|:.:|....|                 .|.||    ::.:.::|....|||:
Human    55 RACLPPGALEELLGTALATQAHG-----------------VSTLG----NSSEGRTWDLPSALLF 98

  Fly   200 SVTVITTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSL 241
            :.:::||.|:|.:.|.:..||...:.||.:|:|..|..:::|
Human    99 AASILTTTGYGHMAPLSPGGKAFCMVYAALGLPASLALVATL 140

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1688	NP_610516.1	Ion_trans_2	<191..247	CDD:285168	17/51 (33%)
CG1688	NP_610516.1	Ion_trans_2	822..896	CDD:285168
KCNK7	NP_203133.1	Ion_trans_2	<90..140	CDD:285168	16/49 (33%)
KCNK7	NP_203133.1	Ion_trans_2	182..>220	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	121	1.000	Inparanoid score	I4753
Isobase	1	0.950	-	0	Normalized mean entropy	S7175
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.810