Protein Alignment trpl and YVC1

DIOPT Version :9

• Sequence 1: NP_476895.1
• Gene: trpl / 36003
• FlyBaseID: FBgn0005614
• Length: 1124
• Species: Drosophila melanogaster
• Sequence 2: NP_014730.2
• Gene: YVC1 / 854255
• SGDID: S000005613
• Length: 675
• Species: Saccharomyces cerevisiae
• Alignment Length: 759
• Identity: 163/759 - (21%)
• Similarity: 281/759 - (37%)
• Gaps: 239/759 - (31%)

  Fly   167 EILRI------LLDRGAAVPV---PHDIRCGCEE-----CVRLTAEDSLRHSLSRVN--IYRALC 215
            :|||:      |:|:  .||:   |:||.|...|     .|:|..|....:...:.|  .|:::.
Yeast    34 QILRVTLNLKYLIDK--VVPIVYDPNDIVCDHSEILSPKVVKLAYEACGGNPKDKANKRKYQSVI 96

  Fly   216 SPSLICLTSNDPIITAFQLS----WELRNLALTEQECK-----SEYMDLRRQCQKFAVDLLDQTR 271
            ..||:.:.....|:...::.    :|.|||| ::|.||     .|..||    |...:.||.:..
Yeast    97 IFSLLKVCEWYSILATMEVHNAKLYETRNLA-SQQLCKLLIEREETRDL----QFLFMQLLLRRY 156

  Fly   272 TSNELAIILNYDPQMSSYEPGDRMSLTRLVQAISYKQKKFVAHSNIQQLLSSIW-----YDGL-- 329
            ..||     |.:.|    ||     |..|..|........:..|..|:.|..||     .:||
Yeast   157 VINE-----NDEDQ----EP-----LNALELATDMHCTTVIGSSGFQRCLKWIWRGWIVQNGLDP 207

  Fly   330 PGFRRKSIVDKVICIAQ---VAVLFPLYCLIYMCAPNCRTGQLMRKPFMKFLIHASSYLFFLFIL 391
            ..|.:...:.:|..|:.   |.:..|:|                    ..:|....|:| ||.:.
Yeast   208 TTFIKDDSLAEVSLISHFNPVRLKAPVY--------------------QNYLQMIFSFL-FLGLY 251

  Fly   392 ILVSQRADDDFVRIFGTTRMKKELAEQELRQRGQTPSKLELIVVMYVIGFVWEEVQEIFAVGMKS 456
            .||....|.:.|:.|                     ..||.|..::..||:.:|:.:::.:|. :
Yeast   252 TLVVNGKDSERVQSF---------------------DLLESIFYVFNTGFILDELTKLYYIGY-A 294

  Fly   457 YLRNMWNFIDFLRNSLYVSVMCLRAFAYIQQATEIARDPQMAYIPREKWHDFDPQLIAEGLFAAA 521
            :| :.||..:.....:....|..||.:.         .|..|....|.|.....::::   .||.
Yeast   295 HL-SFWNLFNDTTYLIITFAMGFRAMSV---------TPLNAKYSSEDWDKISYRVLS---CAAP 346

  Fly   522 NVFSALKLVHLFSINPHLGPLQISLGRMVIDIVKFFFIYTLVLFAFACGLNQLLWYFAALEKSKC 586
            .|:|.| |::|.| ...:|.:.:.|..|:.:.:.|||:..|::..|..|       |..|:.:
Yeast   347 FVWSRL-LLYLES-QRFIGIMLVILKHMMKESIVFFFLLFLIMIGFTQG-------FLGLDSA-- 400

  Fly   587 YVLPGGEADWGSHGDSCMKWRRFGNLFESSQSLFWASFGMVGLDDFELSGIKSYT-RFWGLLMFG 650
                .|:.|        :.....|||          :..::||..|::  .:.:. .:..:|.:|
Yeast   401 ----DGKRD--------ITGPILGNL----------TITVLGLGSFDV--FEEFAPPYAAILYYG 441

  Fly   651 SYSVINVIVLLNLLIAMMSNSYAMIDEHSDTEWKFARTKLWMSYF----EDSATLP--------- 702
            .|.:::|| |||:|||:.|.:|..:.:::|.|:....::..:.|.    ||....|
Yeast   442 YYFIVSVI-LLNILIALYSTAYQKVIDNADDEYMALMSQKTLRYIRAPDEDVYVSPLNLIEVFMT 505

  Fly   703 PPFNVLPSVK---------------WVIRIFRKSSKTIDRQRSKKRKE-QEQFSEYD-------- 743
            |.|.:||..:               :::.|..|.::...|.:..:.|. .:..:|||
Yeast   506 PIFRILPPKRAKDLSYTVMTIVYSPFLLLISVKETREARRIKYNRMKRLNDDANEYDTPWDLTDG 570

  Fly   744 ----------------------NIMRSLVWRYVAA---MHRK---------------FE--NNPV 766
                                  ...|||..:..|.   :|.|               ||  :|..
Yeast   571 YLDDDDGLFSDNRNSGMRATQLKNSRSLKLQRTAEQEDVHFKVPKKWYKNVKKCSPSFEQYDNDD 635

  Fly   767 SEDDINEVKSEIN--TMRYEML-----EIFENSGMDVSSANKKE 803
            :|||..|.|.|:.  |.:.|.|     ::.|.  :|:.  :|||
Yeast   636 TEDDAGEDKDEVKELTKKVENLTAVITDLLEK--LDIK--DKKE 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trpl	NP_476895.1	trp	48..784	CDD:273311	156/733 (21%)
		ANK	48..195	CDD:238125	13/41 (32%)
		ANK repeat	78..114	CDD:293786
		ANK repeat	134..177	CDD:293786	5/15 (33%)
		TRP_2	187..246	CDD:285535	15/69 (22%)
		DUF2031	<706..>805	CDD:299055	32/171 (19%)
YVC1	NP_014730.2	Ion_trans	235..470	CDD:395416	68/326 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910