| Sequence 1: | NP_476895.1 | Gene: | trpl / 36003 | FlyBaseID: | FBgn0005614 | Length: | 1124 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_536321.1 | Gene: | Trpc4 / 84494 | RGDID: | 621276 | Length: | 977 | Species: | Rattus norvegicus |
| Alignment Length: | 1034 | Identity: | 399/1034 - (38%) |
|---|---|---|---|
| Similarity: | 582/1034 - (56%) | Gaps: | 159/1034 - (15%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 42 EKKFLLAVERGDMPNVRRILQKALRHQHININCMDPLGRRALTLAIDNENLEMVELLVVMGVETK 106
Fly 107 DALLHAINAEFVEAVELLLEHEELIYKEGEPYSWQKV-----DINTAMFAPDITPLMLAAHKNNF 166
Fly 167 EILRILLDRGAAVPVPHDIRCGCEECVRLTAEDSLRHSLSRVNIYRALCSPSLICLTSNDPIITA 231
Fly 232 FQLSWELRNLALTEQECKSEYMDLRRQCQKFAVDLLDQTRTSNELAIILNYDPQMSSYEPGDRMS 296
Fly 297 LTRLVQAISYKQKKFVAHSNIQQLLSSIWYDGLPGFRRKSIVDKVICIAQVAVLFPLYCLIYMCA 361
Fly 362 PNCRTGQLMRKPFMKFLIHASSYLFFLFILILVSQRADDDFVRIFGTTRMKKELAEQELRQRGQT 426
Fly 427 PSKLELIVVMYVIGFVWEEVQEIFAVGMKSYLRNMWNFIDFLRNSLYVSVMCLRAFAYIQQATEI 491
Fly 492 ARDPQMAYIPREKWHDFDPQLIAEGLFAAANVFSALKLVHLFSINPHLGPLQISLGRMVIDIVKF 556
Fly 557 FFIYTLVLFAFACGLNQLLWYFAALEKSKCYVLPGGEADWGSHGDSCMKWRR-FGNLFESSQSLF 620
Fly 621 WASFGMVGLDDFELSGIKSYTRFWGLLMFGSYSVINVIVLLNLLIAMMSNSYAMIDEHSDTEWKF 685
Fly 686 ARTKLWMSYFEDSATLPPPFNVLPS-------VKWV--------IRIFRKSSKTIDRQRSKKRKE 735
Fly 736 QEQFSEYDNIMRSLVWRYVAAMHRKFENNP-VSEDDINEVKSEINTMRYEMLEIFE--------- 790
Fly 791 -NSGMDVSSANKKER-----------------------QPRPRRIKVWERRLMKG----FQVAPV 827
Fly 828 QNGCELDAFGNVNGQGEMQEIKVESIPSKPAKETAKERFQRVARTVLLQSTTHKWNVVLRAAKDS 892
Fly 893 QIGRCTKNERKSLQNLGRAIEEAKRLIMLNPGCPSGRESPIRIEFEDEKTSTL-LELLNQISAEI 956
Fly 957 SDSEKPKIRPIWRPPLKTVPARAMAANNTRSLTAPELKISRK--SSPAPTPTPTPGVSH 1013 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| trpl | NP_476895.1 | trp | 48..784 | CDD:273311 | 350/757 (46%) |
| ANK | 48..195 | CDD:238125 | 76/151 (50%) | ||
| ANK repeat | 78..114 | CDD:293786 | 22/35 (63%) | ||
| ANK repeat | 134..177 | CDD:293786 | 18/47 (38%) | ||
| TRP_2 | 187..246 | CDD:285535 | 37/58 (64%) | ||
| DUF2031 | <706..>805 | CDD:299055 | 37/147 (25%) | ||
| Trpc4 | NP_536321.1 | trp | 17..749 | CDD:273311 | 353/763 (46%) |
| ANK 1 | 31..60 | 11/26 (42%) | |||
| ANK | 64..>168 | CDD:238125 | 55/110 (50%) | ||
| ANK 2 | 69..97 | 16/27 (59%) | |||
| Multimerization domain. /evidence=ECO:0000250 | 87..172 | 41/91 (45%) | |||
| ANK repeat | 122..167 | CDD:293786 | 18/44 (41%) | ||
| TRP_2 | 176..235 | CDD:285535 | 37/58 (64%) | ||
| Multimerization domain. /evidence=ECO:0000250 | 254..304 | 28/49 (57%) | |||
| Binds to ITPR1, ITPR2 and ITPR3. /evidence=ECO:0000250 | 615..977 | 107/407 (26%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 767..790 | 4/22 (18%) | |||
| PDZ-binding domain. /evidence=ECO:0000250 | 975..977 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C166341885 | |
| Domainoid | 1 | 1.000 | 274 | 1.000 | Domainoid score | I1701 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG3609 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 801 | 1.000 | Inparanoid score | I473 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D355630at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000660 | |
| OrthoInspector | 1 | 1.000 | - | - | mtm8940 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_102173 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 1 | 1.000 | - | - | X802 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 12 | 11.700 | |||||