| Sequence 1: | NP_476895.1 | Gene: | trpl / 36003 | FlyBaseID: | FBgn0005614 | Length: | 1124 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_004612.2 | Gene: | TRPC6 / 7225 | HGNCID: | 12338 | Length: | 931 | Species: | Homo sapiens |
| Alignment Length: | 841 | Identity: | 291/841 - (34%) |
|---|---|---|---|
| Similarity: | 452/841 - (53%) | Gaps: | 126/841 - (14%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 38 LLLEEKKFLLAVERGDMPNVRRILQKALRHQHININCMDPLGRRALTLAIDNENLEMVELLVVMG 102
Fly 103 VETK--DALLHAINAEFVEAVELLLEHEELIYKEGEPYS------------WQKVDINTAMFAPD 153
Fly 154 ITPLMLAAHKNNFEILRILLDRGAAVPVPHDIRCGCEECVRLTAEDSLRHSLSRVNIYRALCSPS 218
Fly 219 LICLTSNDPIITAFQLSWELRNLALTEQECKSEYMDLRRQCQKFAVDLLDQTRTSNELAIILNYD 283
Fly 284 PQMSSYEPGD--RMSLTRLVQAISYKQKKFVAHSNIQQLLSSIWYDGLPGFRRKSIVDKVICIAQ 346
Fly 347 VAVLFPLYCLIYMCAPNCRTGQLMRKPFMKFLIHASSYLFFLFILILVSQRADDDFVRIFGTTRM 411
Fly 412 KKEL----AEQELRQRGQTPSKLELIVVMYVIGFVWEEVQEIFAVGMKSYLRNMWNFIDFLRNSL 472
Fly 473 YVSVMCLRAFAY---------------IQQATEIARDPQMAY--IPREKWHDFDPQLIAEGLFAA 520
Fly 521 ANVFSALKLVHLFSINPHLGPLQISLGRMVIDIVKFFFIYTLVLFAFACGLNQLLWYFAALEKSK 585
Fly 586 CYVLPGGEADWGSHGDSCMKWRRFGNLFESSQSLFWASFGMVGLDDFELSGIKSYTRFWGLLMFG 650
Fly 651 SYSVINVIVLLNLLIAMMSNSYAMIDEHSDTEWKFARTKLWMSYFEDSATLPPPFNVLPS----- 710
Fly 711 ------VKWVIRIFRKSSK-----------------------------TIDRQRSKKRKE----- 735
Fly 736 QEQF---------SEYDNIMRSLVWRYVAAMHRKFENNPVSEDDINEVKSEINTMRYEMLE 787 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| trpl | NP_476895.1 | trp | 48..784 | CDD:273311 | 282/826 (34%) |
| ANK | 48..195 | CDD:238125 | 57/160 (36%) | ||
| ANK repeat | 78..114 | CDD:293786 | 17/37 (46%) | ||
| ANK repeat | 134..177 | CDD:293786 | 15/54 (28%) | ||
| TRP_2 | 187..246 | CDD:285535 | 26/58 (45%) | ||
| DUF2031 | <706..>805 | CDD:299055 | 29/136 (21%) | ||
| TRPC6 | NP_004612.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..26 | ||
| trp | 82..897 | CDD:273311 | 287/836 (34%) | ||
| ANK 1 | 97..126 | 11/31 (35%) | |||
| ANK 2 | 132..161 | 12/28 (43%) | |||
| ANK repeat | 132..159 | CDD:293786 | 12/26 (46%) | ||
| ANK repeat | 161..185 | CDD:293786 | 11/25 (44%) | ||
| ANK 3 | 163..189 | 11/27 (41%) | |||
| ANK repeat | 212..247 | CDD:293786 | 14/34 (41%) | ||
| ANK 4 | 218..247 | 13/28 (46%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3609 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.770 | |||||