Protein Alignment trpl and Trpc7

DIOPT Version :9

• Sequence 1: NP_476895.1
• Gene: trpl / 36003
• FlyBaseID: FBgn0005614
• Length: 1124
• Species: Drosophila melanogaster
• Sequence 2: XP_017455952.1
• Gene: Trpc7 / 282822
• RGDID: 628820
• Length: 904
• Species: Rattus norvegicus
• Alignment Length: 819
• Identity: 269/819 - (32%)
• Similarity: 413/819 - (50%)
• Gaps: 163/819 - (19%)

  Fly    41 EEKKFLLAVERGDMPNVRRILQKALRHQHININCMDPLGRRALTLAIDNENLEMVELLVVMG--V 103
            ||::||.:.|.|::|.||::|:::   :.:|.||:|.:|:.||.||:.||:||:.|||:...  .
  Rat   140 EEERFLDSAEYGNIPVVRKMLEES---KTLNFNCVDYMGQNALQLAVGNEHLEVTELLLKKENLA 201

  Fly   104 ETKDALLHAINAEFVEAVELLLEH---------------EELIYKEGEPYSWQKVDINTAMFAPD 153
            ...||||.||:..:|..||.:|.|               :||  ::.:.|::   |.:...|:.|
  Rat   202 RVGDALLLAISKGYVRIVEAILSHPAFAQGQRLTLSPLEQEL--RDDDFYAY---DEDGTRFSHD 261

  Fly   154 ITPLMLAAHKNNFEILRILLDRGAAVPVPHDIRCGCEECVRLTAEDSLRHSLSRVNIYRALCSPS 218
            |||::||||...:||:.|||.:||.:..|||..|.|.||.....:||..||.||:|.|:.|.|.:
  Rat   262 ITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSRSRMNAYKGLASAA 326

  Fly   219 LICLTSNDPIITAFQLSWELRNLALTEQECKSEYMDLRRQCQKFAVDLLDQTRTSNELAIILNYD 283
            .:.|:|.||::||.:||.||..||..|.|.|::|..|..||:.|.|.:||..|.:.|:..|||.|
  Rat   327 YLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVGVLDLCRDTEEVEAILNGD 391

  Fly   284 PQMSSYEPGDRMSLTRLVQAISYKQKKFVAHSNIQQLLSSIWYDGLPGFRRKSIVDKVICIAQVA 348
            ..:..:....|.||:|:..||.|:.||.
  Rat   392 VNLQVWSDHHRPSLSRIKLAIKYEVKKL------------------------------------- 419

  Fly   349 VLFPLYCLIYMCAPNCRTGQLMRKPFMKFLIHASSYLFFLFILILVSQRADDDFVRIFGTTRMKK 413
                              |:.:|.|||||:.||.|:..||.:|::   .|.|   |..|...:..
  Rat   420 ------------------GRTLRSPFMKFVAHAVSFTIFLGLLVV---NASD---RFEGVKTLPN 460

  Fly   414 E----LAEQELRQRGQTPSKLELIVVMYVIGFVWEEVQEIFAVGMKSYLRNMWNFIDFLRNSLYV 474
            |    ..:|..|.:....|..|::::.:|:|.:|.|.:||:..|.:.|:.::||.:||...|::|
  Rat   461 ETFTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSVFV 525

  Fly   475 SVMCLRAFA-------------YIQQAT--EIARDPQMAYI--PREKWHDFDPQLIAEGLFAAAN 522
            :....|..|             |:|..|  .::..|::||.  .|:||...|||:|:|||:|.|.
  Rat   526 ASFTARFMAFLKASEAQLYVDQYVQDVTLHNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAV 590

  Fly   523 VFSALKLVHLFSINPHLGPLQISLGRMVIDIVKFFFIYTLVLFAFACGLNQLLWYFAALEKSKCY 587
            |.|..::.::...|...|||||||||.|.||.||..|:.:|..||..|:..|..|:...:.:..
  Rat   591 VLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPA- 654

  Fly   588 VLPGGEADWGSHGDSCMKWRRFGNLFESSQSLFWASFGMVGLDDFELSGIKSYTRFWGLLMFGSY 652
                                 |..:.||.::|||:.||:..:....|.....:....|.:::|.|
  Rat   655 ---------------------FTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVY 698

  Fly   653 SVINVIVLLNLLIAMMSNSYAMIDEHSDTEWKFARTKLWMSYFEDSATLPPPFNVLPSVK----- 712
            :|..|:||||:||||::|||..|:|.:|.||||||.|||:|||::..|||.|||::||.|
  Rat   699 NVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYL 763

  Fly   713 ------WVIRIFRKSSKTIDRQ------RSKKRKEQEQ--------------FSE---YDNIMRS 748
                  .:|::.:..:|..:..      .||.||.:.|              ||:   |..||:.
  Rat   764 IMRIKMCLIKLCKSKAKRCENDLEMGMLNSKFRKTRYQAGMRNSENLTANSTFSKPTRYQKIMKR 828

  Fly   749 LVWRYVAAMHRKFENNPVSEDDINEVKSEINTMRYEMLE 787
            |:.|||.......||:.|:|.::.|:|.:|:::|||:||
  Rat   829 LIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLE 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trpl	NP_476895.1	trp	48..784	CDD:273311	261/807 (32%)
		ANK	48..195	CDD:238125	60/163 (37%)
		ANK repeat	78..114	CDD:293786	17/37 (46%)
		ANK repeat	134..177	CDD:293786	16/42 (38%)
		TRP_2	187..246	CDD:285535	26/58 (45%)
		DUF2031	<706..>805	CDD:299055	32/116 (28%)
Trpc7	XP_017455952.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3609
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.770