Protein Alignment ZBTB41 and br

DIOPT Version :9

• Sequence 1: NP_919290.2
• Gene: ZBTB41 / 360023
• HGNCID: 24819
• Length: 909
• Species: Homo sapiens
• Sequence 2: NP_001162638.2
• Gene: br / 44505
• FlyBaseID: FBgn0283451
• Length: 1011
• Species: Drosophila melanogaster
• Alignment Length: 882
• Identity: 155/882 - (17%)
• Similarity: 251/882 - (28%)
• Gaps: 302/882 - (34%)

Human    77 LNDDRQKQPSFCDLLIIVEGKEFSAHKVVVAVGSSYFHACLSKNP-STDVVTLDHVTHSVFQHLL 140
            |.||.    :|.|:.:..||:...||:||::..|.||...|...| ...|:.|..|.......|:
  Fly    25 LRDDE----AFVDVTLACEGRSIKAHRVVLSACSPYFRELLKSTPCKHPVILLQDVNFMDLHALV 85

Human   141 EFLYTSEFFVYKYEIPLVLEAAKFLDIIDAVKLLNNENVAPFHSELTE-----KSSPEETLNELT 200
            ||:|..|..|::..:...|:.|:.|    .|..|..:.....||.|.:     .|.....||..|
  Fly    86 EFIYHGEVNVHQKSLQSFLKTAEVL----RVSGLTQQQAEDTHSHLAQIQNLANSGGRTPLNTHT 146

Human   201 GRLSNNHQCKF-----CSRHFCYK----------KSLENH--------LAKTHRSLLLG----KK 238
            ..|.:.|....     .|..|..:          .||.:|        :|..|||....    ..
  Fly   147 QSLPHPHHGSLHDDGGSSTLFSRQGAGSPPPTAVPSLPSHINNQLLKRMAMMHRSSAAAAAEETS 211

Human   239 HGLKMLERS-------------------------------------FSARRSKRNRKCPVKFDD- 265
            |..|.|..|                                     ||..:...|...|...::
  Fly   212 HAFKRLRGSDNSLPLSGAVGSGSNNNSPDLPPLHARSASPQQTPADFSTIKHHNNNNTPPLKEEK 276

Human   266 ----TSDDEQESGDGSDNLNQENFDKEKSDRNDSEDPGSEYNAEEDELEEE------------MS 314
                |.:....:|:|:.|..........||:..|..|.....|..|:::.|            .:
  Fly   277 RNGPTGNGNSGNGNGNGNGASNGNGISISDKLGSLTPSPLARAGADDVKSEPMDMVCSNNNANAN 341

Human   315 DEYSDIEEQSEKDHN------------DAEEEPEAGDSVGNVH---------------------- 345
            ||:|: :...|.|.|            .:..:.|.||.:.:.|
  Fly   342 DEHSN-DSTGEHDANRSSSGDGGKGSLSSGNDEEIGDGLASHHAAPQFIMSPAENKMFHAAAFNF 405

Human   346 EGLTPVVIQNSNKKILQ------CPKCDKTFDRIGKYESHTRVHTGEKPFECDICHQRYSTKSNL 404
            ..:.|..:...|.::.|      .|:...|    |...|...|..|..           .|.||.
  Fly   406 PNIDPSALLGLNTQLQQSGDLAVSPQGGST----GSLLSGVIVPGGSG-----------GTPSNS 455

Human   405 TVHRKKHSNETEFHKKE-------------HKCPYCNKLHASKKTLAKHVKRFHPENAQEFISIK 456
            :.:...:::..:..|.|             |..|:.|.                |:..||
  Fly   456 SSNNNNNNSNNQQQKVEQQSSPHQLLQQQHHSTPHTNS----------------PQLKQE----- 499

Human   457 KTKSESWKC---DI-----CKKSFTR----RPHLEEH-------MILHSQDKPFKCTYCEEHFKS 502
            :.||....|   |:     .::|.:|    .|....|       ...|.:::..:.....|..:.
  Fly   500 QPKSGGGSCKSSDLHIAAGSERSLSRSSQGMPDAGGHSATPSPTAAYHKRERERERERERERERE 564

Human   503 RFARLKHQEKF------------------HLGPFPCDICGRQFNDTGNLKRHIECTHGGKRKWTC 549
            |...|.|:...                  |.|..|..:
  Fly   565 RERSLDHERDLERPGGTGSPPPPPPSHHSHFGQHPLSL--------------------------- 602

Human   550 FICGKSVRERTTLKEHLRIHSGEKPHLCSICGQSFRHGSSYRLHLRVHHDDKRYECDECGKTFIR 614
                        |..|.::|:..  |..|.......|..::..|        .:.....|.. :.
  Fly   603 ------------LPSHHQLHATH--HELSAAAAHHAHAHAHAAH--------AHALARAGSP-ME 644

Human   615 HDHLTKHKKIH---SGEKAHQCEECGKCFGRRDH--------LTVHYKSVHLGEKVWQKYKA-TF 667
            |.||..|::..   ||..:......|:..|....        .:|..:.|....::...... ..
  Fly   645 HHHLLHHRRASLSPSGAVSSASGAGGRGGGAGGPGGPGGSLLSSVRAQDVAQANRLLLPLPLNAC 709

Human   668 HQCDVCKKIFKGKSSLEMHFRTHSGEKPYK---CQICNQSFRIKKTLTKHLVIHSDARPFNCQHC 729
            |:||||.|:...|.:|:.| :.....:|..   |.:|::.||...:|..|..|:
  Fly   710 HRCDVCGKLLSTKLTLKRH-KEQQHLQPLNNAVCNLCHKVFRTLNSLNNHKSIY----------- 762

Human   730 NATFKRKDKLKYHIDHVHEIKSPDDPLSTSEEKLVSL 766
               .:|:.....:..|...:.....|.|...:.|.||
  Fly   763 ---HRRQKNHHSYFHHGAGVSQAGSPGSRLHQSLSSL 796

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZBTB41	NP_919290.2	BTB_POZ_ZBTB41	66..179	CDD:349535	30/102 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	252..344		22/120 (18%)
		C2H2 Zn finger	363..383	CDD:275368	4/19 (21%)
		C2H2 Zn finger	391..411	CDD:275368	3/19 (16%)
		C2H2 Zn finger	424..442	CDD:275368	2/17 (12%)
		C2H2 Zn finger	465..485	CDD:275368	6/38 (16%)
		C2H2 Zn finger	493..510	CDD:275368	3/16 (19%)
		C2H2 Zn finger	520..541	CDD:275368	0/20 (0%)
		C2H2 Zn finger	549..569	CDD:275368	2/19 (11%)
		C2H2 Zn finger	577..597	CDD:275368	3/19 (16%)
		zf-C2H2	603..625	CDD:395048	5/21 (24%)
		C2H2 Zn finger	605..625	CDD:275368	5/19 (26%)
		C2H2 Zn finger	633..651	CDD:275368	3/25 (12%)
		C2H2 Zn finger	670..687	CDD:275368	7/16 (44%)
		C2H2 Zn finger	698..718	CDD:275368	6/19 (32%)
		C2H2 Zn finger	726..743	CDD:275368	1/16 (6%)
br	NP_001162638.2	BTB	22..118	CDD:279045	30/100 (30%)
		BTB	33..118	CDD:197585	26/88 (30%)
		C2H2 Zn finger	712..729	CDD:275368	8/17 (47%)
		C2H2 Zn finger	742..763	CDD:275368	7/34 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910