DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sqa and CPK1

DIOPT Version :9

Sequence 1:	NP_001260832.1	Gene:	sqa / 36002	FlyBaseID:	FBgn0259678	Length:	888	Species:	Drosophila melanogaster
Sequence 2:	NP_196107.1	Gene:	CPK1 / 830366	AraportID:	AT5G04870	Length:	610	Species:	Arabidopsis thaliana

Alignment Length:	532	Identity:	153/532 - (28%)
Similarity:	244/532 - (45%)	Gaps:	93/532 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DSEPEGVLEPAFP--MRDVT---------INRNVDAHKHYDVLG-EVGRGKFGTVYKCRDKANGL 58
            :|:|:...:|..|  |:.|:         :.|..:..|.:..|| ::|:|:|||.:.|.:|..|.
plant   110 ESKPDPPAKPKKPKHMKRVSSAGLRTESVLQRKTENFKEFYSLGRKLGQGQFGTTFLCVEKTTGK 174

  Fly    59 QLAAKFVPIPKR-----EDKRNVEREVEIMNSLQHHL-----IIQLYAAYEYQKMMCVVLELIEG 113
            :.|.|  .|.||     ||..:|.||::||    |||     :|.:..|||....:.:|:|...|
plant   175 EFACK--SIAKRKLLTDEDVEDVRREIQIM----HHLAGHPNVISIKGAYEDVVAVHLVMECCAG 233

  Fly   114 GELFDRVVDDEFVLTERVCRVFIRQVCEAMAFIHGNGIVHLDLKPENILVLTQ-KGNRIKIIDFG 177
            ||||||::.... .|||......|.:...:...|..|::|.||||||.|.::: :.:.:|.||||
plant   234 GELFDRIIQRGH-YTERKAAELTRTIVGVVEACHSLGVMHRDLKPENFLFVSKHEDSLLKTIDFG 297

  Fly   178 LARKFDPDKRLRVLFGTPEFVAPEVVNFDCISYG--TDMWSVGVICYVLISGLSPFMGENDIETM 240
            |:..|.||.....:.|:|.:|||||:.   ..||  .|:||.|||.|:|:||:.||..|.:....
plant   298 LSMFFKPDDVFTDVVGSPYYVAPEVLR---KRYGPEADVWSAGVIVYILLSGVPPFWAETEQGIF 359

  Fly   241 SNVTIAKYDFEDECFNGISPECLDFIAKLLAKDLSTRMTAAECMKHKWLQ------QRPATAATA 299
            ..|.....||..:.:..||....|.:.|:|.:|...|:||.:.:.|.|:|      .:|..:|..
plant   360 EQVLHGDLDFSSDPWPSISESAKDLVRKMLVRDPKKRLTAHQVLCHPWVQVDGVAPDKPLDSAVL 424

  Fly   300 TPITKAASAASKSRLKSVSPVTAPSESSEDSTETIE-----DEDDEEEVAVQQAKQKDQQ----- 354
            :.: |..||.:|.: |....|.|.|.|.|:.....|     |.|...::..::.|...::
plant   425 SRM-KQFSAMNKFK-KMALRVIAESLSEEEIAGLKEMFNMIDADKSGQITFEELKAGLKRVGANL 487

  Fly   355 QDEELANLCGDAELEN------KELDATKDNLKNFIVRWETHPNSPYV-FDVEGNVIAPLSETSY 412
            ::.|:.:|...|:::|      ||..|...:| |.|.| |.|..:.:. ||.:|        :.|
plant   488 KESEILDLMQAADVDNSGTIDYKEFIAATLHL-NKIER-EDHLFAAFTYFDKDG--------SGY 542

  Fly   413 PHPRRTHGADSLSSSRVCSPSPCDSISTLTDDERGD--IEDLPEEDESRSAENE------SPRSV 469
            ..|      |.|..:       |:...  .:|.|.:  :.|:.::::.|...||      .....
plant   543 ITP------DELQQA-------CEEFG--VEDVRIEELMRDVDQDNDGRIDYNEFVAMMQKGSIT 592

  Fly   470 ATPINESREKLF 481
            ..|:....||.|
plant   593 GGPVKMGLEKSF 604

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqa	NP_001260832.1	S_TKc	34..289	CDD:214567	96/268 (36%)
sqa	NP_001260832.1	STKc_MLCK	40..289	CDD:271005	94/261 (36%)
CPK1	NP_196107.1	STKc_CAMK	149..407	CDD:270687	96/267 (36%)
CPK1	NP_196107.1	PTZ00184	444..586	CDD:185504	35/166 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810