DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sqa and CPK4

DIOPT Version :9

Sequence 1:	NP_001260832.1	Gene:	sqa / 36002	FlyBaseID:	FBgn0259678	Length:	888	Species:	Drosophila melanogaster
Sequence 2:	NP_192695.1	Gene:	CPK4 / 826541	AraportID:	AT4G09570	Length:	501	Species:	Arabidopsis thaliana

Alignment Length:	541	Identity:	143/541 - (26%)
Similarity:	232/541 - (42%)	Gaps:	88/541 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 PAFPMRDVTINRNVDAHKHYDVLGEVGRGKFGTVYKCRDKANGLQLAAKFVPIPK---REDKRNV 76
            |..|...|..........||.:..::|:|:|||.|.|.:|::....|.|.:|..|   |||..:|
plant     6 PRRPSNSVLPYETPRLRDHYLLGKKLGQGQFGTTYLCTEKSSSANYACKSIPKRKLVCREDYEDV 70

  Fly    77 EREVEIMNSL-QHHLIIQLYAAYEYQKMMCVVLELIEGGELFDRVVDDEFVLTERVCRVFIRQVC 140
            .||::||:.| :|..::::...||....:.:|:|:.||||||||:| .:...:||.....|:.:.
plant    71 WREIQIMHHLSEHPNVVRIKGTYEDSVFVHIVMEVCEGGELFDRIV-SKGCFSEREAAKLIKTIL 134

  Fly   141 EAMAFIHGNGIVHLDLKPENILVLTQKGN-RIKIIDFGLARKFDPDKRLRVLFGTPEFVAPEVVN 204
            ..:...|..|::|.||||||.|..:...: ::|..||||:..:.|.:.|..:.|:|.:|||||:.
plant   135 GVVEACHSLGVMHRDLKPENFLFDSPSDDAKLKATDFGLSVFYKPGQYLYDVVGSPYYVAPEVLK 199

  Fly   205 FDCISYGTDMWSVGVICYVLISGLSPFMGENDIETMSNVTIAKYDFEDECFNGISPECLDFIAKL 269
             .|.....|:||.|||.|:|:||:.||..|.:......:...|.||:.:.:..||....|.|.|:
plant   200 -KCYGPEIDVWSAGVILYILLSGVPPFWAETESGIFRQILQGKIDFKSDPWPTISEGAKDLIYKM 263

  Fly   270 LAKDLSTRMTAAECMKHKWLQQRPATAATATPITKAASAASKSRLKSVSP----------VTAPS 324
            |.:....|::|.|.:.|.|:....|..      .|....|..||||..|.          |.|..
plant   264 LDRSPKKRISAHEALCHPWIVDEHAAP------DKPLDPAVLSRLKQFSQMNKIKKMALRVIAER 322

  Fly   325 ESSEDSTETIE-----DEDDEEEVAVQQAKQ-----KDQQQDEELANLCGDAELEN-------KE 372
            .|.|:.....|     |.|:...:..::.|.     ..:..:.|:.:|...|:::|       :.
plant   323 LSEEEIGGLKELFKMIDTDNSGTITFEELKAGLKRVGSELMESEIKSLMDAADIDNSGTIDYGEF 387

  Fly   373 LDAT-----KDNLKNFIVRWETHPNSPYVFDVEGNVIAPLSETSYPHPRRTHGADSLSSSRVCSP 432
            |.||     .:..:|.:|.:.       .||.:|:....:.|.                .:.|:.
plant   388 LAATLHINKMEREENLVVAFS-------YFDKDGSGYITIDEL----------------QQACTE 429

  Fly   433 -SPCDSISTLTDDERGDIEDLPEEDESRSAENESPRSVATPINESREKLFPTVATSSPSTPTPQH 496
             ..||   |..||...:| ||..:.:...:|..:.......:..||               |.::
plant   430 FGLCD---TPLDDMIKEI-DLDNDGKIDFSEFTAMMKKGDGVGRSR---------------TMRN 475

  Fly   497 LFNENFDEFSGSQSTAQQQRS 517
            ..|.|..|..|.:.|:...:|
plant   476 NLNFNIAEAFGVEDTSSTAKS 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqa	NP_001260832.1	S_TKc	34..289	CDD:214567	90/259 (35%)
sqa	NP_001260832.1	STKc_MLCK	40..289	CDD:271005	89/253 (35%)
CPK4	NP_192695.1	STKc_CAMK	24..282	CDD:270687	91/259 (35%)
CPK4	NP_192695.1	PTZ00184	319..461	CDD:185504	30/168 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900