DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sqa and mylk3

DIOPT Version :9

Sequence 1:	NP_001260832.1	Gene:	sqa / 36002	FlyBaseID:	FBgn0259678	Length:	888	Species:	Drosophila melanogaster
Sequence 2:	NP_001099057.1	Gene:	mylk3 / 561635	ZFINID:	ZDB-GENE-030131-3497	Length:	715	Species:	Danio rerio

Alignment Length:	291	Identity:	142/291 - (48%)
Similarity:	205/291 - (70%)	Gaps:	6/291 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MIYIDDSEPEGVLEPAFPMRDVTINRNVDAHKHYDV--LGEVGRGKFGTVYKCRDKANGLQLAAK 63
            ::.||||.|   |...|..|.|:. :.|..:.:|.|  :..:|.|:||.|:||.:.::||.||||
Zfish   373 LLIIDDSPP---LPAPFDHRIVSA-KQVPINSYYAVNPVEVLGGGRFGQVHKCAELSSGLTLAAK 433

  Fly    64 FVPIPKREDKRNVEREVEIMNSLQHHLIIQLYAAYEYQKMMCVVLELIEGGELFDRVVDDEFVLT 128
            .:.:...:::..|:.|:.:||.|.|..:||||.|:|.:..:.:::|.:||||||:|::|:.:.||
Zfish   434 IIKVRGMKERDEVKNEIGVMNQLNHVNLIQLYDAFESRTNLTLIMEYVEGGELFERIIDESYQLT 498

  Fly   129 ERVCRVFIRQVCEAMAFIHGNGIVHLDLKPENILVLTQKGNRIKIIDFGLARKFDPDKRLRVLFG 193
            |....||.||:||.:.::|...|:||||||||||.:...||:|||||||||||:.|.::|:|.||
Zfish   499 ELDAIVFTRQICEGVQYLHQQYILHLDLKPENILCVNSTGNQIKIIDFGLARKYRPREKLKVNFG 563

  Fly   194 TPEFVAPEVVNFDCISYGTDMWSVGVICYVLISGLSPFMGENDIETMSNVTIAKYDFEDECFNGI 258
            ||||:||||||:|.:|:.|||||||||.|:|:||||||||:||.|||:|:..||::|:.|.|..:
Zfish   564 TPEFLAPEVVNYDFVSFPTDMWSVGVITYMLLSGLSPFMGDNDAETMNNILHAKWEFDTEAFENV 628

  Fly   259 SPECLDFIAKLLAKDLSTRMTAAECMKHKWL 289
            |.|..|||:.||.....:|::|:.||||.||
Zfish   629 SEEAKDFISSLLVSAKCSRLSASGCMKHSWL 659

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqa	NP_001260832.1	S_TKc	34..289	CDD:214567	130/256 (51%)
sqa	NP_001260832.1	STKc_MLCK	40..289	CDD:271005	128/248 (52%)
mylk3	NP_001099057.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	67..114
		STKc_MLCK3	399..659	CDD:271094	130/259 (50%)
		S_TKc	407..659	CDD:214567	128/251 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000818
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24347
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4277
SonicParanoid	1	1.000	-	-		X2697
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.940